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Gramicidin D
go.drugbank.com/drugs/DB00027ApprovedInvestigationalGramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus … Gramcidins are 15 residue peptides with alternating D and L amino acids, which assemble inside of the hydrophobic interior of the cellular lipid bilayer to form a β-helix.
Mixtures: Polysporin for Kids, Antibiotic Cream for KidsColfosceril palmitate
go.drugbank.com/drugs/DB09114ApprovedWithdrawn[T70] It was developed by Burroughs Wellcome and it was FDA approved on August 6, 1990.[L1109] Nowadays colfosceril palmitate is under the state of canceled post-marketing.
Ataluren
go.drugbank.com/drugs/DB05016ApprovedWithdrawnThis drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any indications. … Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk.
Epcoritamab
go.drugbank.com/drugs/DB16672ApprovedInvestigational[L46516,L46556] In September 2023, epcoritamab was also approved in the EU for the same indication. … Although this regimen is effective in up to 60% of patients, patients with relapsed or refractory DLBCL have poor outcomes.
Sacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigationalMetastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. … approval for the treatment of mTNBC patients who have undergone two or more prior therapies.
Secretin human
go.drugbank.com/drugs/DB09532ApprovedInvestigationalThe hormone is produced from the enterochromaffin cells in the duodenum in response to the duodenal content with the pH less than 4.5 [L1875]. … The main action of secretin is to stimulate the pancreas to secrete pancreatic juice for pH regulation in the small intestines.
Categories: Tests for Pancreatic FunctionElranatamab
go.drugbank.com/drugs/DB15395ApprovedInvestigational[L47815] On August 14, 2023, the FDA granted accelerated approval to elranatamab for the treatment of multiple myeloma. … It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one
Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15731InvestigationalORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. … feature allows them to be hypoimmunogenic and non-inducible for tumorigenesis.
Aminophylline
go.drugbank.com/drugs/DB01223ApprovedInvestigationalSimilar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD.
Categories: Drugs for Obstructive Airway Diseases, Compounds used in a research, industrial, or household settingEthiodized oil
go.drugbank.com/drugs/DB00965ApprovedInvestigationalEthiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil.
Categories: Compounds used in a research, industrial, or household setting