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Displaying results 1531 - 1540 of 5504 in total
  1. Drug

    Miltefosine

    go.drugbank.com/drugs/DB09031
    ApprovedInvestigational

    It can be administered topically or orally and is only indicated in patients aged 12 years or older. … It is currently the only recognized oral agent used to treat visceral, cutaneous, and mucosal forms of leishmaniasis, a neglected tropical disease.

  2. Drug

    Tocopherol

    go.drugbank.com/drugs/DB11251
    ApprovedInvestigational

    They present strong antioxidant activities, and it is determined as the major form of vitamin E. … [A32436] It is currently under the list of substances generally recognized as safe (GRAS) in the FDA for the use of human consumption.[L2114]

    Categories: Vitamin E, tocopherol (vit E)Products: VITAMINA E VCA
  3. Drug

    Flurandrenolide

    go.drugbank.com/drugs/DB00846
    Approved

    It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p733)

  4. Drug

    Segesterone acetate

    go.drugbank.com/drugs/DB14583
    Approved

    It mediates progestational activity 100 times higher than that of [progesterone] [A37092]. … It is commonly sold under the brand names Nestorone and Elcometrine and serves as an active component in hormonal contraceptives.

  5. Drug

    Sodium lauryl sulfate

    go.drugbank.com/drugs/DB00815
    Approved

    It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl. … It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity.

  6. Drug

    Dehydrocholic acid

    go.drugbank.com/drugs/DB11622
    Approved

    It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.

    Mixtures: Duchol Ect
  7. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    It is currently being tested in Phase III trials. [2] Although pixantrone has not yet received FDA approval in the United States, it has been granted conditional marketing approval by the European Union … It also inhibits doxorubicinol formation in human myocardium. [3] As a result, it is believed to be less cardiotoxic while still exerting efficacy.

  8. Drug

    Volanesorsen

    go.drugbank.com/drugs/DB15067
    Approved

    [L16621] This drug is not commonly prescribed as it is used as an adjunct to diet in patients at high risk for pancreatitis, who have had inadequate response to triglyceride lowering therapy. … [L16621] It is indicated to treat familial chylomicronemia, a genetic condition that prevents breakdown of triglycerides and chylomicrons.

  9. Drug

    Iopodic acid

    go.drugbank.com/drugs/DB09333
    ApprovedWithdrawn

    [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque property. It was developed and filed to the FDA by the company BRACCO. … This drug was approved on March 15, 1962 but it is nowadays discontinued from the FDA and Health Canada.

  10. Drug

    Cyclothiazide

    go.drugbank.com/drugs/DB00606
    Approved

    As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. … It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.