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Cyclacillin
go.drugbank.com/drugs/DB01000ApprovedA cyclohexylamido analog of penicillanic acid.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseIsavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigationalThis formulation also avoids the use of a cyclodextrin vehicle for solubilization required for intravenous administration of other antifungals such as voriconazole and posaconazole, eliminating concerns … Isavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis
Products: CRESEMBA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 200MGCefoperazone
go.drugbank.com/drugs/DB01329ApprovedInvestigationalWithdrawnCefoperazone is a semisynthetic broad-spectrum cephalosporin proposed to be effective against <i>Pseudomonas</i> infections. … It is a third-generation antiobiotic agent and it is used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis
Mixtures: CEFPER 1 g POWDER FOR INJECTION, DUOPERAZONE 1G POWDER FOR INJECTIONCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseLecanemab
go.drugbank.com/drugs/DB14580ApprovedInvestigationalLecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology … [A253962,L44547] On January 6, 2023, lecanemab was granted accelerated approval by the FDA for the treatment of Alzheimer’s Disease.[L44547] It was granted full FDA approval on July 6, 2023.
Gemtuzumab ozogamicin
go.drugbank.com/drugs/DB00056ApprovedInvestigationalOn September 1 2017, gemtuzumab ozogamicin was again approved for the treatment of adults with newly diagnosed CD33-positive acute myeloid leukemia but with a lower dosing regimen and a different schedule … It is also indicated for the treatment of patients aged 2 years and older with CD33-positive AML who have experienced a relapse or who have not responded to initial treatment (refractory) [L941].
Products: MYLOTARG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 5MG/VIALIpecac
go.drugbank.com/drugs/DB13293ApprovedWithdrawnIpecac is obtained from the plant _Cephaelis ipecacuanha_ and contains a number of emetic alkaloids including emetine and cephaeline. … [L1113] The FDA does not have currently any approved product containing ipecac, however, ipecac as an ingredient is accepted to be sold over the counter in packages of 1 fluid ounce (30 ml) for the emergency
Mixtures: Trousse Antipoison Pour Enfants LiqCeforanide
go.drugbank.com/drugs/DB00923ApprovedIt has a longer elimination half-life than any currently available cephalosporin.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseGestrinone
go.drugbank.com/drugs/DB11619ApprovedGestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and … Gestrinone was developed in the early 1970s and was tested clinically as a weekly oral contraceptive in Europe and North America.
Categories: Hormonal Contraceptives for Systemic UsePhenyl salicylate
go.drugbank.com/drugs/DB11071ApprovedThese are polycyclic compounds that is either a polyphenolic compound composed of two or more monocyclic aromatic units linked by an ester bond (depside), or a compound containing the depsidone structure … It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate (found in [DB00945] ).
Mixtures: Uro-LMotixafortide
go.drugbank.com/drugs/DB14939ApprovedInvestigational[L48141] It has also been investigated alongside [pembrolizumab] for the treatment of pancreatic cancer.[A261481] … Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation.