DB01000ApprovedSmall molecule
A cyclohexylamido analog of penicillanic acid.
- Mechanism
- Curator reviewed
The bactericidal activity of cyclacillin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cyclacillin is stable in the presence of a variety of b-lactamases, including penicillinases and some cephalosporinases.
- Primary indication
- For the treatment of bacterial infections caused by susceptible organisms.Curator reviewed
- Formula / weight
- C15H23N3O4S · 341.426 g/mol (avg)
- Also known as
- Ciclacillin
Resolves to
Clinical / RWD
Structure
InChIKey
HGBLNBBNRORJKI-WCABBAIRSA-NSMILES[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C1(N)CCCCC1)C(O)=OTransporters
What you can answer from here — as of September 23, 2026
4Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
3TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Cyclacillin, and which of those have an active Phase 3 trial?
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