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Displaying results 1541 - 1550 of 10000 in total
  1. Drug

    Hydrocortisone succinate

    go.drugbank.com/drugs/DB14545
    ApprovedInvestigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersProducts: SOLU-CORTEF® 100 MG POLVO PARA INYECCION, SOLU-CORTEF FOR INJECTION 100 mg/vial
  2. Drug

    Praziquantel

    go.drugbank.com/drugs/DB01058
    ApprovedInvestigationalVet approved

    Praziquantel is a pyrazino-isoquinolein derivative from the thioxantonic group used as a broad anthelmintic spectrum. … [A263201] The efficacy of praziquantel in treating parasitic flatworms infection with low cost (~US$0.20 drug cost to treat a child) makes it an integral to WHO's plan to eliminate schistosomiasis by 2030

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: DISTOCIDE TABLET 600 mg, CISTICID ® 600MG
  3. Drug

    Polyvinyl alcohol

    go.drugbank.com/drugs/DB11060
    Approved

    Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. … Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826].

    Mixtures: FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİ, SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 MLCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Tiopronin

    go.drugbank.com/drugs/DB06823
    Approved

    Tiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria. … It is similar to d-penicillamine in use and efficacy, but offers the advantage of far less adverse effects.

    Categories: N-substituted Glycines, Genito Urinary System and Sex HormonesProducts: Thiola EC
  5. Drug

    Pindolol

    go.drugbank.com/drugs/DB00960
    ApprovedInvestigational

    [A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348] … Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-ol, 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol
  6. Drug

    ISIS 2503

    go.drugbank.com/drugs/DB16181
    Investigational

    ISIS 2503 is under investigation in clinical trial NCT00004193 (ISIS 2503 in Treating Patients With Metastatic And/or Locally Recurrent Colorectal Cancer).

    Synonyms: H-ras antisense oligodeoxynucleotide isis 2503
  7. Drug

    Factor XIII (human)

    go.drugbank.com/drugs/DB12909
    ApprovedInvestigational

    Within the body, FXIII circulates as a heterotetramer composed of 2 A-subunits and 2 B-subunits (A2B2)[A32363]. … As the half-life of endogenous Factor XIII is long (5-11 days), prophylactic therapy with the replacement of FXIII can be given every 4-6 to maintain hemostasis[A32363].

    International brands: Fibrogammin PProducts: Corifact 250, Fibrogammin 250 IE Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung
  8. Drug

    Apalutamide

    go.drugbank.com/drugs/DB11901
    ApprovedInvestigational

    In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846]. … Approximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InducersProducts: ERLEADA ®TABLETAS RECUBIERTAS 60 MG
  9. Drug

    HZT-501

    go.drugbank.com/drugs/DB05369
    Investigational

    HZT-501 is under investigation by Horizon Therapeutics, Inc., a privately held biopharmaceutical company. … HZT-501 is a combination product including ibuprofen and the acid reducing agent famotidine.

  10. Drug

    Ioxaglic acid

    go.drugbank.com/drugs/DB09313
    ApprovedWithdrawn

    Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during angiography, arteriography … This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures.

    Mixtures: Hexabrix 200, Hexabrix 200Categories: X-Ray Contrast Activity, X-Ray Contrast Media, Iodinated