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Idelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalIn contrast to the other class IA PI3Ks p110α and p110β, p110δ is principally expressed in leukocytes (white blood cells) and is important for the function of T cells, B cell, mast cells and neutrophils … co-morbidities, while in the treatment of FL and SLL it is intended to be used in patients who have received at least two prior systemic therapies.
Butorphanol
go.drugbank.com/drugs/DB00611ApprovedIllicitVet approvedIt is used in the management of severe pain.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide belongs to the class of drugs known as _thiazolides_. … Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].
Oxolamine
go.drugbank.com/drugs/DB13216ApprovedOxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant [L5416]. It is listed as a prescription drug in New Zealand legislation [L5419]. … Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflamation [L5422].
Mixtures: OLEDRO HOT D TEK DOZLUK EFERVESAN GRANÜL İÇEREN POŞET, 12 ADET, OLEDRO HOT D TEK DOZLUK EFERVESAN GRANÜL İÇEREN POŞET, 6 ADETDipyridamole
go.drugbank.com/drugs/DB00975ApprovedInvestigationalDipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Mixtures: AGGRENOX ® CAPSULAS DE LIBERACION RETARDADAProducts: DIPIRIDAMOL GRAGEAS DE 75 MGDolasetron
go.drugbank.com/drugs/DB00757ApprovedInvestigationalDolasetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative … This drug is not shown to have activity at other known serotonin receptors, and has low affinity for dopamine receptors.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AntagonistsGallamine triethiodide
go.drugbank.com/drugs/DB00483ApprovedWithdrawnThe actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac … It should be used cautiously in patients at risk from increased heart rate but may be preferred for patients with bradycardia. (From AMA Drug Evaluations Annual, 1992, p198)
Synonyms: Trietioduro de galamina, Triéthiodure de GallamineAlverine
go.drugbank.com/drugs/DB01616ApprovedInvestigationalWithdrawnIt can also be used to help relieve period pain. … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions.
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: BENAZEPRIL E IDROCLOROTIAZIDE AUROBINDO, BENAZEPRIL E IDROCLOROTIAZIDE AUROBINDOCategories: Agents Acting on the Renin-Angiotensin SystemFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalHMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. … Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.