Gallamine triethiodide is a nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation. A synthetic nondepolarizing blocking drug.
- Mechanism
- Curator reviewed
It competes with acetylcholine (ACh) molecules and binds to muscarinic acetylcholine receptors on the post-synaptic membrane of the motor endplate. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. It blocks the action of ACh and prevents activation of the muscle contraction process. It can also act on nicotinic presynaptic acetylcholine receptors which inhibits the release of ACh.
- Primary indication
- For use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilationCurator reviewed
- Formula / weight
- C30H60I3N3O3 · 891.5291 g/mol (avg)
- First approval
- Canada, 2000
- Code names
- F 2559 · HL 8583 · RP 3697
Resolves to
REEUVFCVXKWOFE-UHFFFAOYSA-KSMILES[I-].[I-].[I-].CC[N+](CC)(CC)CCOC1=CC=CC(OCC[N+](CC)(CC)CC)=C1OCC[N+](CC)(CC)CCWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Gallamine triethiodide, and which of those have an active Phase 3 trial?
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