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Displaying results 1551 - 1560 of 7604 in total

Drug
Lubiprostone
go.drugbank.com/drugs/DB01046
ApprovedInvestigational
Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastroi...
Categories: Drugs for Constipation
Drug
Sulfacetamide
go.drugbank.com/drugs/DB00634
Approved
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Categories: Anti-Acne Preparations for Topical Use, Antiinfectives for Treatment of Acne
Drug
Regdanvimab
go.drugbank.com/drugs/DB16405
ApprovedWithdrawn
Trials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 began in mid-2020. … [L39140] It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate.
Categories: Antiinfectives for Systemic Use, Approved Treatments for COVID-19
Drug
Phenoxymethylpenicillin
go.drugbank.com/drugs/DB00417
ApprovedInvestigationalVet approved
surgical procedures of the upper respiratory tract, except for those who are at an elevated risk for endocarditis. … Phenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK.[A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin].
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseInternational brands: Apo-Pen-VK, Betapen-VK
Drug
Damoctocog alfa pegol
go.drugbank.com/drugs/DB14700
ApprovedInvestigational
In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized.
Drug
Deuruxolitinib
go.drugbank.com/drugs/DB18847
ApprovedInvestigational
[A264113] On July 26, 2024, deuruxolitinib was approved by the FDA for the treatment of severe alopecia areata. … Deuruxolitinib is a deuterated form of [ruxolitinib] that selectively inhibits Janus kinases (JAK) JAK1 and JAK2.
Categories: Bile Salt Export Pump Inhibitors
Drug
Elvitegravir
go.drugbank.com/drugs/DB09101
ApprovedInvestigational
On September 24, 2014, the FDA approved the single pill form of elvitegravir. … Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
Drug
Mercaptopurine
go.drugbank.com/drugs/DB01033
ApprovedInvestigational
It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Categories: Drugs for Obstructive Airway Diseases
Drug
Nizatidine
go.drugbank.com/drugs/DB00585
Approved
The drug is used for the treatment of duodenal ulcers.
Categories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)
Drug
Uridine triacetate
go.drugbank.com/drugs/DB09144
Approved
It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). … When used for the treatment or prevention of toxicity associated with fluorouracil and other antimetabolites, uridine triacetate is utilized for its ability to compete with 5-fluorouracil (5-FU) metabolites