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Displaying results 1561 - 1570 of 10000 in total
  1. Drug

    Dalpiciclib

    go.drugbank.com/drugs/DB17456
    Investigational

    Synonyms: Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino)-, Cdk4/6 inhibitor shr6390Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    MAK-683

    go.drugbank.com/drugs/DB19205
    Investigational

    Synonyms: 1,2,4-TRIAZOLO(4,3-C)PYRIMIDIN-5-AMINE, N-((5-FLUORO-2,3-DIHYDRO-4-BENZOFURANYL)METHYL)-8-(2-METHYL-3-PYRIDINYL)-, N-((5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)(1,2,4)triazolo(4,3-c)pyrimidin-5-amine
  3. Drug

    2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamide

    go.drugbank.com/drugs/DB07988
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Tapentadol

    go.drugbank.com/drugs/DB06204
    ApprovedInvestigational

    Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. … [A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011.

    Synonyms: 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol, PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  5. Drug

    7-methyl-5'-guanylic acid

    go.drugbank.com/drugs/DB03593
    Experimental

    Synonyms: 7-methyl-5'-guanylic acid, 7-methylguanosine 5'-phosphateCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Mixtures: Prosera Soothing Hand Sanitizer, P-Care MGCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Delamanid

    go.drugbank.com/drugs/DB11637
    ApprovedInvestigational

    Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies with narrow therapeutic index [A31968]. … Spontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 coenzymes responsible for bioactivation of delamanid contributes to this effect [L1407].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo(2,1-B)(1,3)oxazole, (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazole
  8. Drug

    Azapropazone

    go.drugbank.com/drugs/DB07402
    ApprovedWithdrawn

    Synonyms: 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione, 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazineCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Raloxifene

    go.drugbank.com/drugs/DB00481
    ApprovedInvestigational

    [A4979,T28] Exhibiting tissue-specific effects distinct from [estradiol], raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM. … However, it has a negligible effect on altering the development and progression of breast cancer itself.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone
  10. Drug

    beta-D-Ribose-5-phosphate

    go.drugbank.com/drugs/DB04352
    Experimental

    Synonyms: 5-O-phosphono-β-D-ribofuranose, β-D-ribofuranose 5-phosphate