Dalpiciclib

DB17456InvestigationalSmall molecule

Dalpiciclib: Overview.

Mechanism: Pharmacologically active on Cyclin-dependent kinase 6 and Cyclin-dependent kinase 4
Curator reviewed
Formula / weight: C₂₅H₃₀N₆O₂ · 446.555 g/mol (avg)
Also known as: Cdk4/6 inhibitor shr6390 · Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-piperidinyl)-2-pyridinyl)amino)-
Code names: SHR-6390

Resolves to

Compound

Structure

InChIKeySGJLSPUSUBJWHO-UHFFFAOYSA-NSMILESCC(=O)C1=C(C)C2=C(N=C(NC3=CC=C(C=N3)C3CCNCC3)N=C2)N(C2CCCC2)C1=O

Targets

What you can answer from here — as of September 13, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

103Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Dalpiciclib, and which of those have an active Phase 3 trial?

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