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Displaying results 1561 - 1570 of 10000 in total
  1. Drug

    Halothane

    go.drugbank.com/drugs/DB01159
    ApprovedVet approvedWithdrawn

    A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly.

  2. Drug

    Ziconotide

    go.drugbank.com/drugs/DB06283
    ApprovedInvestigational

    synthesized without loss of proper bond formation or structural elements. … [A202829, A202835, A202838, A202841, A202850, A202859, L13389] Ziconotide was granted FDA approval on December 28, 2004 for marketing by TerSera therapeutics LLC. under the name Prialt.

    Categories: Compounds used in a research, industrial, or household setting, Analgesics, Non-Narcotic
  3. Drug

    Lasofoxifene

    go.drugbank.com/drugs/DB06202
    ApprovedInvestigationalWithdrawn

    It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. … Ligand Pharmaceuticals signed a license agreement with Sermonix Pharmaceuticals for the development and commercialization of oral lasofoxifene in the USA.

    Categories: Sex Hormones and Modulators of the Genital System
  4. Drug

    Tetrabenazine

    go.drugbank.com/drugs/DB04844
    Approved

    It is a monoamine depletor and used as symptomatic treatment of chorea associated with Huntington's disease. FDA approved on August 15, 2008. … A drug formerly used as an antipsychotic but now used primarily in the symptomatic treatment of various hyperkinetic disorders.

    Synonyms: 1,2,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one
  5. Drug

    Eugenol

    go.drugbank.com/drugs/DB09086
    ApprovedInvestigational

    There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache. … Its exact mechanism of action is unknown, however, it has been shown to interfere with action potential conduction.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Olopatadine

    go.drugbank.com/drugs/DB00768
    Approved

    An ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. … It is a structural analog of [doxepin], which has a minimal anti-allergic activity.

    Categories: Histamine H1 Antagonists, Non-SedatingProducts: OLOPHARM-O, OLOFTAL UD
  7. Drug

    Alosetron

    go.drugbank.com/drugs/DB00969
    ApprovedWithdrawn

    Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer due to numerous reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes.

    Synonyms: 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
  8. Drug

    Pindolol

    go.drugbank.com/drugs/DB00960
    ApprovedInvestigational

    [L32353] Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]

    Synonyms: 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-olCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Beta Blocking Agents, Non-Selective
  9. Drug

    Isatuximab

    go.drugbank.com/drugs/DB14811
    ApprovedInvestigational

    granted Orphan Drug designation and approved on March 2nd, 2020, for the treatment of multiple myeloma. … [L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma.

    Categories: CD38 (Clusters of Differentiation 38) inhibitors
  10. Drug

    Ouabain

    go.drugbank.com/drugs/DB01092
    Approved

    A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. … It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.

    Categories: Compounds used in a research, industrial, or household setting