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Vorapaxar
go.drugbank.com/drugs/DB09030Approvedof myocardial infarction (MI) or with peripheral arterial disease (PAD). … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history
Ramucirumab
go.drugbank.com/drugs/DB05578ApprovedInvestigationalRamucirumab is indicated for us in advanced gastric or gastro-esophageal junction adenocarcinoma as a single agent or in combination with paclitaxel after prior fluoropyrimidine- or platinum-containing … permeability, and migration of human endothelial cells.
Products: CYRAMZA 500 MG/50 ML İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇEREN FLAKON, 1 ADETIloperidone
go.drugbank.com/drugs/DB04946ApprovedInvestigationalIloperidone is a benzisoxazole [A263557] and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009. … [A263547] Iloperidone is currently used to treat schizophrenia and manic or mixed episodes associated with bipolar disorder.[L50527]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAminophylline
go.drugbank.com/drugs/DB01223ApprovedInvestigationalThe majority of aminophylline medications are discontinued and the remaining medications on the market are in short supply. … Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD.
Categories: combinations of xanthines, Compounds used in a research, industrial, or household settingProducts: AMINOFILINA 240 MG / 10 ML., AMINOPHYLLINE INJECTION 0.25 g/10 mlLithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnThey are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. … The active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSodium acetate
go.drugbank.com/drugs/DB09395ApprovedInvestigationalSodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acet...
Mixtures: OQ-BALANS, OQ-BALANSPhenoxyethanol
go.drugbank.com/drugs/DB11304ApprovedInvestigationalPhenoxyethanol (EU), or PE, is the most commonly used globally-approved preservative in personal care formulations. It is very easy to use in various types of formulations and is chemically stable. … It has also been used in vaccines and shown to inactivate bacteria, and several types of yeast [A32838].
Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, LösungIvacaftor
go.drugbank.com/drugs/DB08820ApprovedInvestigational[A20302] Prior to the development of ivacaftor, management of CF primarily involved therapies for the control of infections, nutritional support, clearance of mucus, and management of symptoms rather … Notably, ivacaftor was the first medication approved for the management of the underlying causes of CF (abnormalities in CFTR protein function) rather than control of symptoms.[A20297]
Ligelizumab
go.drugbank.com/drugs/DB11856InvestigationalInitial trials of ligelizumab suggest a greater efficacy over its predecessor for the treatment of CSU.[A242367] … While the precise pathogenesis of CSU is not entirely clear, autoantibodies against IgE receptors, and sometimes against IgE itself, are thought to exist in 30-40% of patients,[A242362,A242367] and the
Pegfilgrastim
go.drugbank.com/drugs/DB00019ApprovedInvestigationalPegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, [filgrastim]. … [L9779,L9785,L43050] These biosimilars are highly similar to the reference product, Neulasta, in terms of pharmacological and pharmacokinetic profile and conditions of use.
Synonyms: PEG-G-CSF, Pegylated G-CSFCategories: Compounds used in a research, industrial, or household setting