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Displaying results 1581 - 1590 of 5758 in total
  1. Drug

    Interferon Kappa

    go.drugbank.com/drugs/DB15749
    Experimental

    Interferon kappa is a subclass of type I interferon mediating host defence which consists of 207 amino acids and has 30% homology with others of the same class as it consists of a series of cysteine and a 27-amino acid signal peptide con...

  2. Drug

    Trifarotene

    go.drugbank.com/drugs/DB12808
    ApprovedInvestigational

    Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to vitamin ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  3. Drug

    Vaborbactam

    go.drugbank.com/drugs/DB12107
    ApprovedInvestigational

    Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. It has been used in trials investigating the treatment of bacterial infections in subjects with varying degrees of renal insufficiency. In August 2017, ...

  4. Drug

    Degarelix

    go.drugbank.com/drugs/DB06699
    ApprovedInvestigational

    Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. Thi...

  5. Drug

    Reproxalap

    go.drugbank.com/drugs/DB16688
    Investigational

    [L32990] NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.[L32990] … Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis

    Synonyms: NS-2
  6. Drug

    Trifluoperazine

    go.drugbank.com/drugs/DB00831
    Approved

    A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.

    Mixtures: Stelabid No 2, Stelabid No 1Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  7. Drug

    Methylselenocysteine

    go.drugbank.com/drugs/DB12697
    Investigational

    Methylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease.

  8. Drug

    NV-5138

    go.drugbank.com/drugs/DB19180
    Investigational

    NV-5138 is under investigation in clinical trial NCT06235905 (Open-label of SPN-820 in Adults With Major Depressive Disorder).

  9. Drug

    Bevirimat

    go.drugbank.com/drugs/DB06581
    Investigational

    Bevirimat, also known as PA-457 or YK-FH312, is investigated in clinical trials for treating HIV infection. Bevirimat is a solid. … Bevirimat targets the protein gag-pol polyprotein. Bevirimat is derived from a betulinic acid-like compound, first isolated from <i>Syzygium claviflorum</i>, a Chinese herb.

  10. Drug

    Light green SF yellowish

    go.drugbank.com/drugs/DB11183
    Approved

    The maximum absorption of light green SF yellowish is at 630 (422) nm.

    Synonyms: Green No. 2, A F Green No.2Categories: P-glycoprotein inhibitors