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Enfortumab vedotin
go.drugbank.com/drugs/DB13007ApprovedInvestigational[L10836] It is similar to [brentuximab vedotin], another antibody conjugated with MMAE that targets CD-30 instead of Nectin-4. … The clinical development of enfortumab vedotin was the result of a collaboration between Astellas Pharma and Seattle Genetics [A188868] and it was first approved for use in the United States in December
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: PADCEV 20 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADET, PADCEV 30 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN TOZ , 1 ADETDobesilic acid
go.drugbank.com/drugs/DB13529InvestigationalProducts: DOXIUM 1000 MG FILM TABLET, 30 ADET, DOXIUM 1000 MG FILM TABLET, 60 ADETCoagulation Factor IX (Recombinant)
go.drugbank.com/drugs/DB00100ApprovedIt has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. … IX complex), and is instead produced by a genetically engineered Chinese hamster ovary (CHO) cell line that secretes recombinant Factor IX into cell medium that is then processed and purified for use as
Products: OCTANINE® F 500 UI, ALPROLIX® 500 UITinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalTinzaparin is a low molecular weight heparin (LMWH), produced by enzymatic depolymerization of unfractionated heparin from porcine intestinal mucosa. It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500...
Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INJECTION 14, 000 Anti-Xa IU/0.7mlBelatacept
go.drugbank.com/drugs/DB06681ApprovedInvestigationalStructurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. … The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes. It is approved for the treatment of rheumatoid arthritis.
Products: NULOJIX ®250 MG/ VIAL POLVO LIOFILIZADO PARA SOLUCION INYECTABLE INTRAVENOSATropicamide
go.drugbank.com/drugs/DB00809Approved[L32178] Oral tropicamide has been investigated as a potential drug to relieve sialorrhea in patients with Parkinson's Disease.[A229958]
Mixtures: MYDRIASERT 0,28 MG/5,4 MG GÖZ INSERTI ,10 INSERT, Mydrane 0,2 mg/ml + 3,1 mg/ml + 10 mg/ml InjektionslösungProducts: MİDAX %1 GÖZ DAMLASI, ÇÖZELTİ, 10 ML, MİDAX %1 GÖZ DAMLASI, ÇÖZELTİ, 5 MLTelithromycin
go.drugbank.com/drugs/DB00976ApprovedTelithromycin binds to the 50S subunit of the 70S bacterial ribosome and blocks further peptide elongation. … Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: KETEK ® 400 MGMetyrapone
go.drugbank.com/drugs/DB01011ApprovedInvestigationalIt is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A InducersProducts: Metycor 250 mg WeichkapselnEpoprostenol
go.drugbank.com/drugs/DB01240ApprovedInvestigationalThe sodium salt has been also used to treat primary pulmonary hypertension.
Synonyms: (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acidProducts: VELETRI® 1.5 MG, VELETRI®0.5 MGTelbivudine
go.drugbank.com/drugs/DB01265ApprovedWithdrawnTelbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Synonyms: 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracilProducts: SEBIVO (600 MG), SEBIVO 600 MG FILM KAPLI TABLET, 28 ADET