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Phenylephrine
go.drugbank.com/drugs/DB00388ApprovedInvestigationalPhenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil,[L9413] and induce local vasoconstriction.
Mixtures: Members Mark Allergy, Ryna -12 SCategories: Adrenergic alpha-1 Receptor Agonists, Monoamine Oxidase A SubstratesPhenindione
go.drugbank.com/drugs/DB00498ApprovedInvestigationalAn indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects.
Categories: Vitamin K AntagonistsSynonyms: 2-Phenyl-1,3-indandione, 2-phenyl-1,3-diketohydrindeneEstriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedA hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. … Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada.
International brands: Synapause EMixtures: GYNOFLOR 50 MG/0.03 MG VAJİNAL TABLET, 6 ADETKetotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigational[A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is … It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and [azatadine].
Categories: Heterocyclic Compounds, 1-RingProducts: CHETOTIFENE MYLAN GENERICS, SP-TOTIFEN SYRUP 1 mg/5 mlLJP 1082
go.drugbank.com/drugs/DB05446ExperimentalThe target of the LJP 1082's clot-promoting antibodies is a small region on a key blood protein called beta 2-glycoprotein I. … LJP 1082 is a Toleragen that is designed to shut down the B cells that produce antibodies to ß2 GP1.
Categories: Compounds used in a research, industrial, or household settingFenoldopam
go.drugbank.com/drugs/DB00800ApprovedA dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Categories: Heterocyclic Compounds, 2-RingDimethicone
go.drugbank.com/drugs/DB11074ApprovedInvestigationalDimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. … Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants.
Mixtures: PRAMIGEL-S, Pre and Post Sx PouchCategories: Compounds used in a research, industrial, or household settingWarfarin
go.drugbank.com/drugs/DB00682ApprovedInvestigationalWarfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. … Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America.
Synonyms: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarinCategories: 4-Hydroxycoumarins, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexTopotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalIt works by inhibiting DNA topoisomerases, type I.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexSynonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecinNabumetone
go.drugbank.com/drugs/DB00461Approved[label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite acting as a potent COX inhibitor similar in structure to [naproxen]. … Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).
Synonyms: 4-(6-Methoxy-2-naphthalenyl)-2-butanone, 4-(6-Methoxy-2-naphthyl)-2-butanoneMixtures: NuDroxiPAK N-500