Search
Telbivudine
go.drugbank.com/drugs/DB01265ApprovedWithdrawnTelbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil, 2'-Deoxy-L-thymidineImiquimod
go.drugbank.com/drugs/DB00724ApprovedInvestigationalImiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas.
Mixtures: Imiquimod 5% / Levocetirizine Dihydrochloride 1% / Niacinamide 2%, Imiquimod 5% / Salicylic Acid 30% / Tretinoin 0.1%Categories: Heterocyclic Compounds, 2-RingOsimertinib
go.drugbank.com/drugs/DB09330ApprovedInvestigational[A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations are correlated with response to therapy. … Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs due to the presence of specific activating EGFR mutations within the tumour cells.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamideLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigational[A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623] … Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.
Categories: Heterocyclic Compounds, 1-RingProducts: LETROL 2.5 MG FILM TABLET, 30 ADET, LETROKABI 2.5 MG FILM TABLET, 30 ADETSacituzumab govitecan
go.drugbank.com/drugs/DB12893ApprovedInvestigational[A193653] In November 2021 and July 20 2023, sacituzumab govitecan was also approved by the European Commission and Health Canada respectively.[L39372,L47601] … [A193671] One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2 (TROP-2) antibody with the topoisomerase I inhibitor SN-38.
Categories: Trop-2-Directed Monoclonal AntibodiesProducts: TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADETHexamidine
go.drugbank.com/drugs/DB03808ApprovedInvestigationalMixtures: Imazol duo 10 mg/g + 2,5 mg/g CremeProducts: DESOMEDINE EYE DROPS 1 mg/mlCeftobiprole medocaril
go.drugbank.com/drugs/DB14733Approved[L50467] It received its first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and was subsequently approved in the United States with additional indications … for skin and skin structure infections and bacteremia in April 2024.
Categories: Heterocyclic Compounds, 2-RingProducts: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungFelbamate
go.drugbank.com/drugs/DB00949ApprovedFelbamate is an anticonvulsant drug used in the treatment of epilepsy. In particular, in the adult patient population, it can be employed to treat partial seizures (with and without generalization). … Alternatively, it is used to treat partial and generalized seizures associated with Lennox-Gastaut syndrome in children. It has a weak inhibitory effect on GABA receptor binding sites.
Synonyms: 2-phenyl-1,3-propanediol dicarbamate, carbamic acid 2-phenyltrimethylene esterProducts: Taloxa 600 mg/5 ml - orale Suspension, Taloxa 600 mg TablettenVedolizumab
go.drugbank.com/drugs/DB09033ApprovedInvestigational[A261576] Vedolizumab is administered by IV infusion over a period of 30 minutes; after the first dose, it is given again at two and six weeks and then every 8 weeks thereafter. … Vedolizumab is a recombinant humanized IgG1 monoclonal antibody directed against the human lymphocyte α4β7 integrin, a key mediator of gastrointestinal inflammation implicated in diseases like ulcerative
Products: ENTYVIO® 108 MG SOLUCIÓN INYECTABLE, ENTYVIO® (SUBCUTÁNEO) VEDOLIZUMAB 108 MG SOLUCIÓN INYECTABLEPivmecillinam
go.drugbank.com/drugs/DB01605ApprovedInvestigationalPivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa.
Categories: Heterocyclic Compounds, 2-RingProducts: Selexid 200 mg Filmtabletten, Selexid 400 mg film-coated tablets