Search

Displaying results 151 - 160 of 9987 in total
  1. Drug

    Oxymetazoline

    go.drugbank.com/drugs/DB00935
    ApprovedInvestigational

    Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors. … cold, hay fever, and upper respiratory allergies.

    Salts: Oxymetazoline hydrochlorideMixtures: Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool
  2. Drug

    DCLL-9718S

    go.drugbank.com/drugs/DB17392
    Investigational

    DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1).

    Categories: Amino Acids, Peptides, and ProteinsSynonyms: THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer
  3. Drug

    Nefazodone

    go.drugbank.com/drugs/DB01149
    ApprovedWithdrawn

    Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. … On May 20, 2004, Bristol-Myers Squibb discontinued the sale of Serzone in the United States.

    Salts: Nefazodone hydrochlorideCategories: Serotonin and Noradrenaline Reuptake Inhibitors, Serotonin antagonist and reuptake inhibitors (SARIs)
  4. Drug

    Alfuzosin

    go.drugbank.com/drugs/DB00346
    Approved

    The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70. … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow.

    Salts: Alfuzosin hydrochlorideCategories: alfuzosin and finasteride, Genito Urinary System and Sex Hormones
  5. Drug

    Pramocaine

    go.drugbank.com/drugs/DB09345
    Approved

    It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic.

    Salts: Pramoxine hydrochlorideMixtures: Johnson and Johnson First Aid Travel Ready 80 CT, Mineral Oil, Pramoxine Hydrochloride and Zinc Oxide
  6. Drug

    Raxtozinameran

    go.drugbank.com/drugs/DB18228
    ApprovedInvestigational

    Raxtozinameran is also known as Pfizer-BioNTech COVID-19 Vaccine and Comirnaty. … [A273680] Raxtozinameran was first approved by the FDA and EMA through emergency use in December 2020.[L52565,L39272]

    Synonyms: messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised pre-fusion stabilised conformation variant (K982P and V983P) of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)
  7. Drug

    Memantine

    go.drugbank.com/drugs/DB01043
    ApprovedInvestigational

    Almost doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and to 115 million by 2050 [F4366]. … Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD).

    Salts: Memantine hydrochlorideMixtures: Memantine Hydrochloride and Donepezil Hydrochloride, Memantine Hydrochloride and Donepezil Hydrochloride
  8. Drug

    Oxymorphone

    go.drugbank.com/drugs/DB01192
    ApprovedVet approved

    On June 8, 2017, FDA requested Endo Pharmaceuticals to remove the medication from the market due to opioid misuse and abuse risks associated with the product's injectable reformulation. … An opioid analgesic with actions and uses similar to those of morphine, apart from an absence of cough suppressant activity.

    Salts: Oxymorphone hydrochlorideProducts: Oxymorphone Hydrochloride, Oxymorphone hydrochloride
  9. Drug

    Dicyclomine

    go.drugbank.com/drugs/DB00804
    ApprovedInvestigational

    and irritable bowel syndrome. … Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder

    Salts: Dicyclomine hydrochlorideCategories: Alimentary Tract and Metabolism
  10. Drug

    Tepilamide fumarate

    go.drugbank.com/drugs/DB18804
    Investigational

    Synonyms: 2-(diethylamino)-2-oxoethyl and methyl (2e)-but-2-enedioate