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AD-114
go.drugbank.com/drugs/DB18285ExperimentalSynonyms: Human single domain antibody-like protein inhibitor of the chemokine receptor type 4DCLL-9718S
go.drugbank.com/drugs/DB17392InvestigationalDCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). … DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine
Synonyms: THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimerCategories: Proteins, Blood ProteinsGo-6976
go.drugbank.com/drugs/DB17029ExperimentalAn inhibitor of calcium-dependent isoforms of protein kinase C.[A253002,A253007]
Synonyms: 12h-indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-Categories: Protein Kinase C, antagonists & inhibitors, Heterocyclic Compounds, 2-RingLorigerlimab
go.drugbank.com/drugs/DB18942InvestigationalLorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Synonyms: -CHAIN V-J REGION) FUSION PROTEIN WITH PEPTIDE LINKER (GGGSGGGG) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEI, IMMUNOGLOBULIN, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) (HUMAN-MUS MUSCULUS CLONE MG13.78 .KAPPA.Orforglipron
go.drugbank.com/drugs/DB18964ApprovedInvestigationalOrforglipron is a first-in-class oral, non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist. … [L56123] On April 1, 2026, the US FDA granted approval to orforglipron for use alongside diet and exercise to aid in weight reduction in certain patient populations.
Categories: GLP-1 Agonists, Cytochrome P-450 SubstratesSynonyms: -c]pyridin-5-yl]carbonyl]-5-[(4S)-tetrahydro-2,2-dim, 3-[(1S,2S)-1-({2-(4-fluoro-3,5-dimethylphenyl)-3-({3-[3-(4-fluoro-1-methyl-1H-indazol-5-yl)-2-oxo-2,3-dihydro-1H-imidazol-1-yl]-4-methyl-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}carbonyl)-5-[(Gresonitamab
go.drugbank.com/drugs/DB18210InvestigationalSynonyms: IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULINNogapendekin alfa
go.drugbank.com/drugs/DB18740ApprovedInvestigationalNogapendekin alfa is a human IL-15N72D variant. … It is one of the active ingredients in Anktiva, a combination product also containing [inbakicept], where a single inbakicept is complexed with two nogapendekin alfa components.
Categories: Proteins, Recombinant ProteinsSynonyms: Fusion protein consisting of il-15n72d and il-15rasu/fc, Il-15n72d:il-15rec-su/fc soluble complex iCHF5633
go.drugbank.com/drugs/DB18696InvestigationalCHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a … synthetic SP-B analogue.
Categories: Proteins, Membrane ProteinsSynonyms: Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogueVitespen
go.drugbank.com/drugs/DB06400InvestigationalSynonyms: Heat shock protein-peptide complex-96 vaccine, Endoplasmin (human tumor rejection antigen 1)Categories: Proteins, Amino Acids, Peptides, and ProteinsPraconase
go.drugbank.com/drugs/DB05584InvestigationalSynonyms: EXOENZYME C3 TRANSFERASE (CLOSTRIDIUM BOTULINUM VARIANT VX-210) FUSION PROTEIN WITH TRANSPORT PEPTIDE (SYNTHETIC)Categories: Proteins, Bacterial Proteins