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Displaying results 151 - 160 of 10000 in total
  1. Drug

    Pacmilimab

    go.drugbank.com/drugs/DB18873
    Investigational

    Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).

    Synonyms: IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH-LIGAND 1) (HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND CLEAVABLE MOIETY PROTEASE SUBSTRATE-CONTAINING
  2. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]

    Mixtures: Propranolol Hydrochloride and Hydrochlorothiazide, Propranolol Hydrochloride and HydrochlorothiazideCategories: Beta Blocking Agents, Non-Selective, and Thiazides, propranolol and thiazides
  3. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    [Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460] … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics

    Mixtures: Nu-oxycodone/acet, TARGIN 20MG/10MGCategories: oxycodone and naloxone, oxycodone and ibuprofen
  4. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass [L1801]. Docusate can be orally or rectally administered. … Recently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912].

    Mixtures: Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA, UltimateCare ONE NFCategories: Alimentary Tract and Metabolism, Softener and Emollient Laxatives
  5. Drug

    Methotrexate

    go.drugbank.com/drugs/DB00563
    ApprovedInvestigational

    [A180322] Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and non-Hodgkin's lymphoma … [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients

    Categories: Antineoplastic and Immunomodulating AgentsSynonyms: 4-amino-N(10)-methylpteroylglutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
  6. Drug

    Zirconium (89Zr) crefmirlimab berdoxam

    go.drugbank.com/drugs/DB19157
    Investigational

    Synonyms: Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells, conjugated to the chelator desferrioxamine (df) and labeled with the radioisotope zirconium Zr-89)
  7. Drug

    Cenplacel-L

    go.drugbank.com/drugs/DB19188
    Investigational

    Cenplacel-L is under investigation in clinical trial (Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Ischemic Stroke) for the treatment of patients

    Synonyms: CELLULAR IDENTITY: MESENCHYMAL-LIKE STROMAL CELL: CD34-, CD10+, CD105+, AND CD200+.
  8. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and

    Categories: morphine and antispasmodics, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol
  9. Drug

    Hydromorphone

    go.drugbank.com/drugs/DB00327
    ApprovedIllicitInvestigational

    [A176495] The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984.[L5795] … Due to these modifications, it presents a very high potency and comparable side effect profile to the parent compound.

    Categories: hydromorphone and naloxone, hydromorphone and antispasmodicsProducts: HYDROMORPHON-NX 1XTGL 16MG, HYDROMORPHON-NX 1XTGL 4MG
  10. Drug

    Torasemide

    go.drugbank.com/drugs/DB00214
    ApprovedInvestigational

    [A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.[A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257]

    Categories: Non Potassium Sparing DiureticsSynonyms: N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide