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TRGFT-201
go.drugbank.com/drugs/DB23064ApprovedInvestigational[L64070] The HSPCs engraft in the bone marrow to reconstitute the blood and immune system, while the purified Tregs, given before the Tcons, suppress alloreactivity to reduce graft-versus-host disease … [L64070,L64071] Orca-T was approved by the FDA on June 30, 2026 for use in matched-donor hematopoietic stem cell transplantation with a myeloablative preparative regimen, for hematopoietic and immunologic
Peppermint
go.drugbank.com/drugs/DB10984ApprovedPeppermint allergenic extract is used in allergenic testing.
Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic ExtractDesoxyribonuclease
go.drugbank.com/drugs/DB09551ApprovedInvestigationalThe enzyme's cofactor is reported to be magnesium (or manganese) ions, although the optimal concentration of the ion is independent of the enzyme concentration [A31251].
Dosulepin
go.drugbank.com/drugs/DB09167ApprovedInvestigationalDosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South
Categories: Non-Selective Monoamine Reuptake InhibitorsGemtuzumab ozogamicin
go.drugbank.com/drugs/DB00056ApprovedInvestigationalin combination with chemotherapy or on its own [L941]. … By binding to the CD33 antigen on tumors, the cytotoxic agent blocks the growth of cancerous cells and causes cell death.
Tocopherol
go.drugbank.com/drugs/DB11251ApprovedInvestigationalThe classification of the tocopherol molecules is designated depending on the number and position of the methyl substituent in the chromanol ring.
Margetuximab
go.drugbank.com/drugs/DB14967ApprovedInvestigational[A225751, A225756, A225766, A191829, L27986] Margetuximab binds to the same epitope on the HER2 extracellular domain and induces the same effects as [trastuzumab]. … [A225751, A225756, A225766, A191829, L27986] Margextuximab was granted FDA approval on December 16, 2020, and is currently marketed under the trademark MARGENZA™ by MacroGenics, Inc.[L27986]
Edaravone
go.drugbank.com/drugs/DB12243ApprovedInvestigational[L44017] Edaravone was initially granted orphan designation by the European Medicines Agency on June 19, 2015 [L44007] and was under regulatory review in Europe. … However, the drug manufacturer, Mitsubishi Tanabe Pharma, withdrew the Marketing Authorization Application (MAA) for edaravone from the European market on May 24, 2019, in response to the request made
Maralixibat
go.drugbank.com/drugs/DB16226ApprovedInvestigationalIt was granted FDA approval on 29 September 2021. … [L44396] On July 21, 2023, maralixibat was also approved by Health Canada.[L47541]