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Thenalidine
go.drugbank.com/drugs/DB04826ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to concerns involving neutropenia.
Cianidanol
go.drugbank.com/drugs/DB14086ApprovedInvestigationalWithdrawnAn antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
Albuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedSalbutamol is formulated as a racemic mixture of the R- and S-isomers. … Salbutamol is generally used for acute episodes of bronchospasm caused by bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders such as chronic obstructive pulmonary disorder
Lacidipine
go.drugbank.com/drugs/DB09236ApprovedIt is available as once-daily oral tablets containing 2 or 4 mg of the active compound commonly marketed as Lacipil or Motens. It is not currently FDA-approved. … It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure.
Reserpine
go.drugbank.com/drugs/DB00206ApprovedWithdrawnIt has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
Rifaximin
go.drugbank.com/drugs/DB01220ApprovedInvestigationalIt has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of overt hepatic encephalopathy recurrence; as well as diarrhea-predominant irritable bowel … Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered
Pipecuronium
go.drugbank.com/drugs/DB01338ApprovedInvestigationalWithdrawnPipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Detomidine
go.drugbank.com/drugs/DB11556InvestigationalVet approvedDetomidine is an α2-adrenergic agonist that is used as a horse sedative. Normally, it is administered in the salt form, detomidine hydrochloride. … This drug is prescribed by veterinarians and is marketed as _Dormosedan_. Currently, it is only approved by the FDA for use in horses but has been studied for use in other large animals.
Arachidonic Acid
go.drugbank.com/drugs/DB04557ApprovedInvestigationalWithdrawnIt is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides.