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GYM329
go.drugbank.com/drugs/DB18590InvestigationalGYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Synonyms: recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent mannerPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalThe mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesFerric cation
go.drugbank.com/drugs/DB13949ApprovedWithdrawnIron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. Iron is an essential element involved in various metabolic processes, including oxygen transport, deoxyribonucleic acid (D...
Phenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalIt promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Mixtures: PB Hyos, Re-PB HyosCategories: P-glycoprotein inducers, P-glycoprotein substratesIMMU-114
go.drugbank.com/drugs/DB18458InvestigationalIMMU-114 is antibody-drug conjugate consisting of humanized anti-HLA-DR IgG4 monoclonal antibody specific for alpha-chain linked to SN-38 via a CL2A linker.
PF-03463275
go.drugbank.com/drugs/DB11993InvestigationalPF-03463275 has been used in trials studying the treatment of Schizophrenia and Cognitive Impairments Associated With Schizophrenia.
Tinlorafenib
go.drugbank.com/drugs/DB17082InvestigationalTinlorafenib (PF-07284890) is a potent, selective, highly brain-penetrant, small-molecule inhibitor of BRAF V600 mutations.[A253992]
TMC-310911
go.drugbank.com/drugs/DB15623Investigationalboth treatment-naive and PI-experienced patients. … TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available [darunavir].
Oxybenzone
go.drugbank.com/drugs/DB01428ApprovedOxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because...
Mixtures: Kara Vita SPF 29, Kara Vita SPF 30