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Manidipine
go.drugbank.com/drugs/DB09238ApprovedInvestigationalWithdrawnManidipine (INN) is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. … It is selective for vasculature and does not produce effects on the heart at clinically relevant dosages.
Products: IPERTEN 20 MG TABLET, 28 ADETLiothyronine
go.drugbank.com/drugs/DB00279ApprovedInvestigationalVet approvedLiothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. … Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3.
Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADETCategories: combinations of levothyroxine and liothyronineEphedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigationalIt is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine … [A193698] Ephedrine acts as both a direct and indirect sympathomimetic.
Mixtures: ColdaeWon Cold A, ColdaeWon Cough ACategories: Diet ProductsNetupitant
go.drugbank.com/drugs/DB09048ApprovedInvestigationalNetupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy … Netupitant is a neurokinin 1 receptor antagonist. The combination drug is marketed by Eisai Inc. and Helsinn Therapeutics (U.S.) Inc. under the brand Akynzeo.
Rilonacept
go.drugbank.com/drugs/DB06372ApprovedInvestigationalRilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome (FCAS) … Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1.
Categories: Agents reducing cytokine levelsTaletrectinib
go.drugbank.com/drugs/DB18711ApprovedInvestigationalTaletrectinib is an orally available small molecule kinase inhibitor. … [L53308] Gene fusions involving _ROS1_, a proto-oncogene, have been identified as oncogenic drivers in 1-2% of patients with non-small cell lung cancer (NSCLC), in addition to other cancers at variable
Miglustat
go.drugbank.com/drugs/DB00419ApprovedInvestigationalMiglustat was first developed as an anti-HIV agent in the 1990s. … It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids.
Products: ZAVESCA 100 MG KAPSUL, 84 ADETEcabet
go.drugbank.com/drugs/DB05265InvestigationalEcabet is a prescription eye drop for the treatment of dry eye syndrome. … Ecabet is currently marketed in Japan as an oral agent for treatment of gastric ulcers and gastritis.
Categories: Pepsin A, antagonists & inhibitors, Compounds used in a research, industrial, or household settingTirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[A246260] Tirzepatide comprises a 39 amino acid linear synthetic peptide conjugated to a C20 fatty diacid moiety. … Dual GIP/GLP-1 agonists gained increasing attention as new therapeutic agents for glycemic and weight control as they demonstrated better glucose control and weight loss compared to selective GLP-1 receptor
Products: Mounjaro 5 mg/0,5 ml Enjeksiyonluk Çözelti, 1 ADET, Mounjaro 5 mg/0,5 ml Enjeksiyonluk Çözelti, 4 ADETSomatrem
go.drugbank.com/drugs/DB09098ApprovedWithdrawnthese hormone agents have been proven effective at increasing the height of children with or without growth hormone deficiency [A32292]. … Such discussion revolves around whether patients' natural disposition of short stature should be considered a medical condition justifying medical treatment with such hormone therapy - especially when