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Ty800
go.drugbank.com/drugs/DB04989InvestigationalThe Ty800 vaccine was developed using genetic techniques to delete specific genes known to be essential to the virulence of <i>S. typhi</i>. It is being developed by AVANT Immunotherapeutics, Inc. … Ty800 is a vaccine designed to offer rapid, oral, single-dose protection against <i>Salmonella typhi</i>, the cause of typhoid fever.
Scorpion (centruroides) immune Fab2 antivenin (equine)
go.drugbank.com/drugs/DB13905Approved*, *C. l. tecomanus*, and *C. s. suffusus*. … Centruroides (scorpion) Immune F(ab')2 (equine) is a purified preparation of immune globulin F(ab’)2 fragments that are derived from plasma of the horses immunized with venom of *C. noxius*, *C. l. limpidus
Synonyms: Centruroides (scorpion) Immune F(ab')2 (equine), Centruroides (scorpion) immune F(ab')2 (equine) injectionProducts: ALVENO AC 10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET FLAKON+1 ADET ÇÖZÜCÜ AMPUL, ACSERA 5 ML ENJEKSIYONLUK COZELTI KONSANTRESI ICEREN FLAKONPutrescine
go.drugbank.com/drugs/DB01917InvestigationalKnown drug targets of putrescine include putrescine-binding periplasmic protein, ornithine decarboxylase, and S-adenosylmethionine decarboxylase proenzyme. … Putrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines.
Capivasertib
go.drugbank.com/drugs/DB12218ApprovedInvestigationalname TRUQAP, was approved by the FDA for the treatment of adult patients HR-positive, HER2-negative locally advanced or metastatic breast cancer with one or more alterations in PIK3CA/AKT1/PTEN gene(s) … Therefore, targeting the PIK3/AKT pathway presents a promising approach for the treatment of breast cancer, leading to the development of capivasertib, a pan-AKT kinase inhibitor.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsBenzimate
go.drugbank.com/drugs/DB05170ExperimentalThe anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor & Gamble Company beginning in the 1990's. … Benzimate is the lead compound selected from a series of compounds known as benzimidazoles.
LU-31130
go.drugbank.com/drugs/DB05828ExperimentalLU-31130 is a rapid acting therapy developed by H. Lundbeck A/S to treat Psychosis, Schizophrenia and Schizoaffective Disorders. … It provides anti-psychotic characteristic and a low incidence of extrapyramidal and cardiovascular side effects.
Dexchlorpheniramine
go.drugbank.com/drugs/DB13679InvestigationalDexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. … The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions.
Mixtures: CORICIDIN® GOTAS PEDIATRICAS CON ACETAMINOFENCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring1D-myo-inositol 1,4,5-trisphosphate
go.drugbank.com/drugs/DB03401ExperimentalInositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. … Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane.
Synonyms: D-myo-Inositol 1,4,5-trisphosphate, D-myo-Inositol-1,4,5-triphosphateOxaprotiline
go.drugbank.com/drugs/DB09307ExperimentalDextroprotiline is the S or dextro isomer of oxaprotiline (CGP-12,104-A). … Oxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A).
INO-4800
go.drugbank.com/drugs/DB15693InvestigationalINO-4800 is a DNA vaccine containing the full sequence for the SARS-CoV-2 Spike (S) protein in development for immunization against COVID-19. … [A214475] Early _in vitro_ studies using HEK-293T cells demonstrated that the transfection of INO-4800 results in the expression of S protein by human cells.