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Davunetide
go.drugbank.com/drugs/DB12613InvestigationalDavunetide is the first drug to improve memory performance by impacting the mechanisms that lead to physical damage in the brain caused by neurofibrillary tangles, one of the two established pathological
Vinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalHaving an incidence of 429,700 new cases per year worldwide, urothelial carcinoma of the bladder is one of the most common malignancies that mostly affects individuals aged 50–79 years [A32626].
Ipratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigationalIpratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption....
Small nuclear ribonucleoprotein Sm D2
go.drugbank.com/bio_entities/BE0009119TargetHumansComponent of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28076346, PubMed:28502770, PubMed:28781166). … Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161
Synonyms: snRNP core protein D2Pyrethrum extract
go.drugbank.com/drugs/DB11087ApprovedPyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediat...
Mixtures: Care One Lice KillingDihydrolipoyl dehydrogenase
go.drugbank.com/bio_entities/BE0002616TargetPseudomonas putidaThe branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).
Synonyms: E3 component of branched-chain alpha-keto acid dehydrogenase complexPotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form dr...
Mixtures: One-A-day Advance Men's, One-A-day Advance Men'sTGAAC94
go.drugbank.com/drugs/DB06175InvestigationalIn 2007, one patient participating in the clinical trial died and the trial was placed on clinical hold by the FDA.
Cholecystokinin
go.drugbank.com/drugs/DB08862ApprovedInvestigationalWithdrawnCholecystokinin is one of the first gastrointestinal hormones discovered, identified more than 90 years ago due to its ability to stimulate gallbladder contraction in 1928.