Potassium chloride

DB00761ApprovedInvestigationalWithdrawnSmall moleculePotassium Salt

Potassium chloride is a potassium salt used to treat hypokalemia. A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

Chemical structure of Potassium chloride
Mechanism
Curator reviewed
Primary indication
For use as an electrolyte replenisher and in the treatment of hypokalemia.Curator reviewed · 34 structured indications
Formula / weight
ClK · 74.551 g/mol (avg)
First approval
Canada, 1996 · United States, 1969
Also known as
Chloride of potash · Kaliumchlorid · Monopotassium chloride · Muriate of potash · Sylvite
Code names
B1653 · E-508 · INS-508 · INS NO.508 · NSC-77368
Brand names
  • Bi-peglyte
  • Bss
  • Bss Ophthalmic Solution
  • Cardioplegic
  • Citrasate
  • Colyte
  • Dextrose and Electrolyte No. 75
  • Diphen
  • Gavilyte-C
  • Gavilyte-G
  • Gavilyte-H and Bisacodyl
  • Gavilyte-N
  • Glycerolyte 57
  • Golytely
  • H.E.L.P.bicel
  • Hemosate Ultra
  • Ionosol-MB
  • Isolyte P
  • Isolyte S
  • Isolyte S pH 7.4
  • Isoplate
  • K-tab
  • Klor-con
  • Lactated Ringers
  • Moviprep
  • Naturalyte
  • Normosol-R
  • Nulytely
  • Nxstage Pureflow
  • Olimel
  • Peglyte
  • Periolimel
  • Phoxillum
  • Physiolyte
  • Physiosol
  • Plasma-lyte
  • Plasma-lyte 148
  • Plasma-lyte 148 In 5 % Dextrose
  • Plasma-lyte R
  • Plasmalyte A
  • Plegisol
  • Plenvu
  • Pokonza
  • Prismasol
  • Procalamine 3
  • Ringers
  • Suflave
  • Tis-U-sol
  • Trilyte
  • +39 moreShow less

Resolves to

Compound
UNII660YQ98I10CAS7447-40-7ChEMBLCHEMBL1200731ChEBI32588PubChem4873KEGGD02060
Clinical / RWD
RxNorm8591ATCA12BA01ATCB05XA01PharmGKBPA451055
Structure
InChIKeyWCUXLLCKKVVCTQ-UHFFFAOYSA-MSMILES[Cl-].[K+]
Targets
P55011SLC12A2Q13621SLC12A1Q9H2X9SLC12A5Q9UHW9SLC12A6Q9Y666SLC12A7Q9UP95SLC12A4
Transporters
P55011SLC12A2Q13621SLC12A1Q9H2X9SLC12A5Q9UHW9SLC12A6Q9Y666SLC12A7Q9UP95SLC12A4

What you can answer from here — as of September 23, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
6TransportersSubstrate / inhibitor direction, not just membership
Listed above
956Drug interactionsStructured to mechanism, not free text
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330Clinical trialsPhase, status and sponsor resolved per trial
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34Structured indicationsCondition, population, route and combination as fields, not prose
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3ContraindicationsEach with its own population and attribute set
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3,423Marketed productsAcross 11 countries and 448 labellers
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2ATC codesIncluding every combination product, plus 15 drug categories
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39+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Potassium chloride, and which of those have an active Phase 3 trial?

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