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Displaying results 1631 - 1640 of 1804 in total
  1. Drug

    Efmoroctocog alfa

    go.drugbank.com/drugs/DB11607
    ApprovedInvestigational

    Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It ...

  2. Drug

    Caldaret

    go.drugbank.com/drugs/DB06231
    Investigational

  3. Target

    NKG2-D type II integral membrane protein

    go.drugbank.com/bio_entities/BE0010415
    TargetHumans

    Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. … Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected

    Synonyms: NK cell receptor D, NKG2-D-activating NK receptor
  4. Drug

    Josamycin

    go.drugbank.com/drugs/DB01321
    Investigational

    A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

  5. Drug

    Tipapkinogene sovacivec

    go.drugbank.com/drugs/DB06239
    Investigational

  6. Drug

    Glipizide

    go.drugbank.com/drugs/DB01067
    ApprovedInvestigational

    Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various co...

  7. Drug

    Deucravacitinib

    go.drugbank.com/drugs/DB16650
    ApprovedInvestigational

    Unlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity

  8. Target

    Transmembrane anterior posterior transformation protein 1 homolog

    go.drugbank.com/bio_entities/BE0003506
    TargetHumans

    Plays a role in primary cilia formation (PubMed:26365339). May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similari...

    Synonyms: Cytomegalovirus partial fusion receptorFunction: growth hormone-releasing hormone receptor activity
  9. Target

    Ribosome-binding protein 1

    go.drugbank.com/bio_entities/BE0003466
    TargetHumans

    Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane

    Synonyms: Ribosome receptor protein, 180 kDa ribosome receptor homolog
  10. Target

    Natural killer cells antigen CD94

    go.drugbank.com/bio_entities/BE0010559
    TargetHumans

    Immune receptor involved in self-nonself discrimination.

    Synonyms: NK cell receptor, Killer cell lectin-like receptor subfamily D member 1Function: HLA-A specific activating MHC class I receptor activity