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Displaying results 1641 - 1650 of 8696 in total
  1. Target

    B1 bradykinin receptor

    go.drugbank.com/bio_entities/BE0005831
    TargetHumans

    This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation

    Polypeptides: B1 bradykinin receptorSynonyms: BK-1 receptor
  2. Target

    Melanocortin receptor 5

    go.drugbank.com/bio_entities/BE0009684
    TargetHumans

    Order of potency of natural melanocortins in receptor activation is alpha-MSH > ACTH > beta-MSH > gamma-MSH (PubMed:8396929). … G protein-coupled receptor for melanocyte-stimulating hormones (alpha- beta- and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:37524700, PubMed:8396929).

    Polypeptides: Melanocortin receptor 5Function: corticotropin receptor activity
  3. Target

    Thyroid hormone receptor

    go.drugbank.com/bio_entities/BE0009811
    TargetHumans and other mammals

    Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine … Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine

    Polypeptides: Thyroid hormone receptor alpha, Thyroid hormone receptor betaSynonyms: Nuclear receptor subfamily 1 group A member 1, Nuclear receptor subfamily 1 group A member 2
  4. Target

    Olfactory receptor 1D2

    go.drugbank.com/bio_entities/BE0013079
    TargetHumans

    Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. … May also function in olfactory reception

    Polypeptides: Olfactory receptor 1D2Synonyms: Olfactory receptor 17-4, Olfactory receptor OR17-6
  5. Target

    Relaxin receptor 2

    go.drugbank.com/bio_entities/BE0017729
    TargetHumans

    May also be a receptor for Leydig insulin-like peptide (INSL3) … Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP.

    Polypeptides: Relaxin receptor 2Synonyms: Leucine-rich repeat-containing G protein-coupled receptor 8, G protein-coupled receptor 106
  6. Drug

    Naltrexone

    go.drugbank.com/drugs/DB00704
    ApprovedInvestigationalVet approved

    The FDA has approved naltrexone for the treatment of alcohol dependence. … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction.

  7. Drug

    Tretinoin

    go.drugbank.com/drugs/DB00755
    ApprovedInvestigationalNutraceutical

    [A257689] It has been used in dermatology for many years to treat various skin conditions ranging from acne to wrinkles [A257474,A258185] and activates nuclear receptors to regulate epithelial cell growth … [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism.

    Mixtures: AE BAN CREMACategories: Retinoids for cancer treatment, Anti-Acne Preparations for Topical Use
  8. Drug

    Teplizumab

    go.drugbank.com/drugs/DB06606
    ApprovedInvestigational

    [L44096] In April 2026, the FDA approved an expanded indication for teplizumab, lowering the eligible age range from 8 years and older down to 1 year and older for patients with Stage 2 T1D.[L56140] … [A241480,A241500] Targeting T cells can be achieved through antibodies against the T cell receptor (TCR) component CD3.

  9. Drug

    5-fluorouridine

    go.drugbank.com/drugs/DB01629
    Investigational

    5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid.

    Synonyms: 5-Fur
  10. Drug

    Carglumic acid

    go.drugbank.com/drugs/DB06775
    ApprovedInvestigational

    Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. … This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death.

    Products: Carglumsäure Waymade 200 mg Tabletten zur Herstellung einer Suspension zum Einnehmen