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Nitrous acid
go.drugbank.com/drugs/DB09112ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. … There is also research to investigate its applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and Pseudomonas aeruginosa infections.
Categories: Compounds used in a research, industrial, or household settingTick-borne encephalitis vaccine (whole virus, inactivated)
go.drugbank.com/drugs/DB16611ApprovedInvestigationalSome patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. … [A237505] TBE often manifests in a biphasic manner, with patients experiencing a flu-like illness followed by a variable asymptomatic period and then a second phase characterized by various neurological
Ceftobiprole
go.drugbank.com/drugs/DB04918ApprovedWithdrawnThe EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole medocaril in February 2010, recommending the refusal of its marketing authorization in the European … for skin and skin structure infections and bacteremia in April 2024.
Strontium chloride
go.drugbank.com/drugs/DB13987ApprovedWithdrawnStrontium chloride (SrCl2) is a salt of strontium and chloride. … Such strontium chloride toothpaste formulations may subsequently not be available for sale anymore in certain parts of the world [A33167, A33168].
Vortioxetine
go.drugbank.com/drugs/DB09068ApprovedInvestigationalIt is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin … Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional
Categories: Antidepressive Agents Indicated for DepressionHelium
go.drugbank.com/drugs/DB09155ApprovedInvestigationalVet approvedHelium is a second most abundant chemical element in the universe with symbol He and atomic number 2. … It is a colorless, odorless, tasteless, non-toxic, inert, monatomic gas located at the top of the noble gases on the periodic table.
Imdevimab
go.drugbank.com/drugs/DB15940ApprovedInvestigationalImdevimab is a monoclonal antibody combined with [casirivimab] in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. … They are reserved for Emergency Use Authorization (EUA) only.[L23524] In November 2021, the same indication was approved by the EMA.
Categories: Antiinfectives for Systemic Use, Approved Treatments for COVID-19Amivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigationalAmivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic … FDA approved the subcutaneous formulation, RYBREVANT FASPRO™, across all existing and expanded indications of amivantamab, including its use as a first-line, chemotherapy-free combination regimen with
Products: RYBREVANT 350mg/7mL Concentrate for Solution for InfusionAlemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigationalThe dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing.[L43397, L30335] … [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic lymphocytic leukemia (B-CLL).
Products: LEMTRADA Concentrate for Solution for Infusion 12 mg, LEMTRADA CONCENTRATE FOR SOLUTION FOR INFUSION 12 MG/ 1.2 MLOnasemnogene abeparvovec
go.drugbank.com/drugs/DB15528ApprovedInvestigational[A187250] As there is no cure for SMA, onasemnogene abeparvovec is a disease-modifying agent that decelerates the disease progression, improves motor function, and manages the symptoms. … Developed by AveXis, a Novartis company,[A187253] onasemnogene abeparvovec is commonly marketed as Zolgensma®, which is available as a single-dose intravenous infusion.