Strontium chloride is a medication used to treat bone pain in skeletal metastases. SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession.
- Mechanism
- Curator reviewed · 3 references
For dental hypersensitivity, strontium ions in strontium chloride toothpaste formulations appear to relieve pain and sensitivity by blocking fluid flow in dentinal tubules, which are essentially microscopic canals in the dentin. Regular use of such toothpastes maintains the strontium chloride barricading of the tubules despite normal everyday wear, tear, and washing of teeth.
- Primary indication
- When employed as an ingredient in toothpaste formulations, strontium chloride is predominantly indicated for treating teeth hypersensitivity.Curator reviewed · 1 structured indication
- Formula / weight
- Cl2Sr · 158.52 g/mol (avg)
- First approval
- Canada, 1969
- Also known as
- strontium dichloride
- Code names
- 2PX
Resolves to
AHBGXTDRMVNFER-UHFFFAOYSA-LSMILES[Cl-].[Cl-].[Sr++]What you can answer from here — as of September 21, 2026
Which drugs share a target with Strontium chloride, and which of those have an active Phase 3 trial?
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