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Displaying results 1651 - 1660 of 2454 in total
  1. Drug

    Lascufloxacin

    go.drugbank.com/drugs/DB20002
    Experimental

    Lascufloxacin is a small molecule drug. The usage of the INN stem '-oxacin' in the name indicates that Lascufloxacin is a nalidixic acid derivative antibacterial. Lascufloxacin has a monoisotopic molecular weight of 439.17 Da.

    Categories: P-glycoprotein substrates
  2. Drug

    Oxeclosporin

    go.drugbank.com/drugs/DB21134
    Experimental

    Oxeclosporin is a small molecule drug. The usage of the INN stem '-(clo)sporin' in the name indicates that Oxeclosporin is a cyclosporine derivative. Oxeclosporin has a monoisotopic molecular weight of 1261.86 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Befetupitant

    go.drugbank.com/drugs/DB21149
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Befetupitant is a neurokinin NK1​ (substance P) receptor antagonist. Befetupitant has a monoisotopic molecular weight of 565.22 Da.

  4. Drug

    Fantofarone

    go.drugbank.com/drugs/DB20875
    Experimental

    Fantofarone is a small molecule drug. Fantofarone has a monoisotopic molecular weight of 550.25 Da.

    Categories: P-glycoprotein inhibitors
  5. Drug

    Tetracycline

    go.drugbank.com/drugs/DB00759
    ApprovedInvestigationalVet approvedWithdrawn

    Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  6. Drug

    Primidone

    go.drugbank.com/drugs/DB00794
    ApprovedVet approved

    Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. Primidone was developed by J Yule Bogue and H C Carrington in 1949. Primidone was granted FDA Approval on 8 Ma...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inducers
  7. Drug

    Minaprine

    go.drugbank.com/drugs/DB00805
    Approved

    Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant re...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  8. Drug

    Pentoxifylline

    go.drugbank.com/drugs/DB00806
    ApprovedInvestigational

    A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant Pharmaceuticals and APOTEX have been available since the late 1990s.[L30300]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  9. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts...

    Mixtures: PERINDOPRIL E INDAPAMIDE MYLAN GENERICS, PERINDOPRIL E INDAPAMIDE MYLAN GENERICSCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Tadalafil

    go.drugbank.com/drugs/DB00820
    ApprovedInvestigational

    Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. It was first approved in 2003 by the FDA for use ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: TADALAFIL DOC GENERICI