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Amphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalThe antibiotic is without effect on bacteria, rickettsiae, and viruses. … Amphotericin B shows a high order of in vitro activity against many species of fungi.
Categories: Compounds used in a research, industrial, or household settingTafasitamab
go.drugbank.com/drugs/DB15044ApprovedInvestigational[L15307] It must be used in combination with [lenalidomide], as this combination results in greater efficacy as compared to either agent alone.[L15292] … [L15292,A191829] The CD19 surface protein is highly expressed on the surface of B-cells, where it appears to play a role in enhancing B-cell receptor signaling.
Mirdametinib
go.drugbank.com/drugs/DB07101ApprovedInvestigational[L52485] NF1 is an autosomal-dominant genetic condition caused by loss-of-function variants in the _NF1_ tumour suppressor gene,[A265065,A265070] leading to neurofibromin dysfunction and aberrant activation … On February 11, 2025, mirdametinib was approved by the FDA for the treatment of neurofibromatosis type 1 (NF1).
Synonyms: N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE N-((2R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOANILINO)BENZAMIDE, (-)-N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDEAxicabtagene ciloleucel
go.drugbank.com/drugs/DB13915ApprovedInvestigationalAxicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. … [A216163] Axicabtagene ciloleucel was approved by the FDA on October 18th, 2017.
Synonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptorArformoterol
go.drugbank.com/drugs/DB01274ApprovedThe use of arformoterol is pending revision due to safety concerns in regards to an increased risk of severe exacerbation of asthma symptoms, leading to hospitalization as well as death in some patients … It works by relaxing muscles in the airways to improve breathing.
Segesterone acetate
go.drugbank.com/drugs/DB14583ApprovedIt is commonly sold under the brand names Nestorone and Elcometrine and serves as an active component in hormonal contraceptives. … In clinical trials, Annovera™ achieved a 97.3% success in pregnancy prevention [L4246]. Annovera™ is administered as a vaginal ring that is in place for 21 days and removed for 7 days each cycle.
Synonyms: 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetateUrea C-13
go.drugbank.com/drugs/DB09510ApprovedInvestigationalRadiolabelled urea is available in two forms as 13C and 14C. … As the urease enzyme is not present in mammalian cells, the presence of urease (and the products of urea cleavage) in the stomach is evidence that H. pylori bacteria are present.
Ferric sulfate
go.drugbank.com/drugs/DB11171ApprovedIt is produced by the reaction of sulfuric acid and an oxidizing agent. … [A32355, A32356] By the FDA, ferric sulfate is a direct food substance affirmed in the GRAS category (Generally Recognized As Safe).[L2003]
Dosulepin
go.drugbank.com/drugs/DB09167ApprovedInvestigationalIts hydrochloride form is a common active ingredient in different drug formulations. … It is not FDA-approved due to low therpeutic index and significant toxicity in overdose.
Synonyms: (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine, 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepinMetamizole
go.drugbank.com/drugs/DB04817ApprovedInvestigationalWithdrawn[A251805] Metamizole is still used in certain countries in Europe, Asia and South America.[A251805] … [L42975] In 1963, metamizole was withdrawn from the Canadian market and banned in the UK, France, Sweden, Norway and Australia.
Mixtures: BIPASMIN COMPUESTO N, BIPASMIN COMPUESTO N