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Temozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigationalIt is currently marketed under the trademark TEMODAR® by Merck.[L32033] … [L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesSynonyms: 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one, 3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamideCisatracurium
go.drugbank.com/drugs/DB00565ApprovedInvestigational[A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times its neuromuscular blocking potency. … [A243416] Compared to atracurium, cisatracurium produces a lower degree of histamine release.[A253597]
Categories: Heterocyclic Compounds, 2-RingSynonyms: (1r,2r,1'r,2'r)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]Bisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigational[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.
Mixtures: COSİMPREL 5 MG/10 MG FİLM KAPLI TABLET, 30 ADET, SOPRANO 10 MG/25 MG FILM TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPropyphenazone
go.drugbank.com/drugs/DB13524InvestigationalPropyphenazone is a non-steroidal anti-inflammatory agent with analgesic effects.[A275063, A275068]
Mixtures: MINOSET PLUS 250 MG/150 MG/50 MG TABLET, 30 ADET, ZAKMEY PLUS 250 MG/ 150 MG/ 50 MG TABLET , 30 ADETCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-Ring2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamide
go.drugbank.com/drugs/DB07390ExperimentalCategories: Heterocyclic Compounds, 1-RingAvoralstat
go.drugbank.com/drugs/DB12120InvestigationalAvoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.
Synonyms: 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine-2-carboxylic acid, 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine-2-carboxylic acidCategories: Heterocyclic Compounds, 1-RingAPTO-253
go.drugbank.com/drugs/DB17143InvestigationalSynonyms: 1h-imidazo(4,5-f)(1,10)phenanthroline, 2-(5-fluoro-2-methyl-1h-indol-3-yl)-, 2-(5-fluoro-2-methyl-1h-indol-3-yl)-1h-imidazo(4,5-f)(1,10)phenanthrolineCategories: Heterocyclic Compounds, 3-Ring, Heterocyclic Compounds, 1-Ring1,2-Dioleoyl-sn-glycero-3-phospho-L-serine
go.drugbank.com/drugs/DB18573ExperimentalSynonyms: 4,6,10-trioxa-5-phosphaoctacos-19-enoic acid, 2-amino-5-hydroxy-11-oxo-8-(((9z)-1-oxo-9-octadecen-1-yl)oxy)-, 5-oxide, (2s,8r,19z)-, 1,2-dioleoyl-sn-glycero-3-phospho-l-serineZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription.
Mixtures: ABACAVIR .LAMIVUDINA +ZIDOVUDINATABLETAS 750 MG, COMBİVİR 150 MG/300 MG FİLM KAPLI TABLETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesIdarubicin
go.drugbank.com/drugs/DB01177ApprovedInvestigationalAn orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, 4-Demethoxydaunomycin