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Cefamandole
go.drugbank.com/drugs/DB01326ApprovedWithdrawnCefamandole is also known as cephamandole. It is a parenterally administered broad-spectrum cephalosporin antibiotic. It is generally formulated as a formate ester, [cefamandole nafate]. … It is no longer marketed in the United States.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseCorticorelin ovine triflutate
go.drugbank.com/drugs/DB09067ApprovedIt is used as a diagnostic agent to evaluate the status of the pituitary-adrenal axis in the differentiation of a pituitary source from an ectopic source of excessive ACTH secretion. … Corticorelin, available commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human corticotropin-releasing hormone (hCRH), a potent stimulator of adrenocorticotropic
Sodium lauryl sulfate
go.drugbank.com/drugs/DB00815ApprovedSLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes. … It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity.
Alemtuzumab
go.drugbank.com/drugs/DB00087ApprovedInvestigational[L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic lymphocytic leukemia (B-CLL). … The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing.[L43397, L30335]
Clavulanic acid
go.drugbank.com/drugs/DB00766ApprovedInvestigationalVet approved[A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav, or Clavulin.[L7880,L7904,L7910] … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus.
Mixtures: AMOXIPLUS RAT COMP 875/125, AMOXIPLUS RAT COMP 875/125Multipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalLike mesenchymal stem cells, MAPCs are derived from bone-marrow stroma and are non-hematopoietically adherent. … The cells for creation of the product are isolated from a qualified donor and expanded on a large scale and then frozen until use. After administration, the cells are cleared from the body over time.
Iopromide
go.drugbank.com/drugs/DB09156Approved[A260751] Although the mechanism is unclear, women and outpatients tend to have a higher incidence of adverse events compared to other population groups. … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration.
Vardenafil
go.drugbank.com/drugs/DB00862ApprovedCompared to [sildenafil] and [tadalafil], vardenafil is a more potent inhibitor of PDE5; however, its selectivity for other PDE isoforms is lower than the one detected for tadalafil. … [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension has also been evaluated.[A258308]
Categories: Genito Urinary System and Sex HormonesPioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[A19759] Thiazolidinediones, including pioglitazone, have fallen out of favor in recent years due to the presence of multiple adverse effects and warnings regarding their use (e.g. congestive heart … [L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence
Vildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigational[L32813] Vildagliptin is currently under investigation in the US. … It is marketed as Galvus.[L32803] Vildagliptin is also available as Eucreas, a fixed-dose formulation with metformin for adults in who do not adequately glycemic control from monotherapy.