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Proscillaridin
go.drugbank.com/drugs/DB13307Experimental] and triggering cell death and blocking cell proliferation of glioblastoma cell lines [A27194]. … Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima).
Categories: Compounds used in a research, industrial, or household settingInfluenza A virus A/Hong Kong/2671/2019 NIB-121 (H3N2) antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15710ApprovedWithdrawnInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Mixtures: Fluarix Tetra Injektionssuspension in einer FertigspritzeCyclothiazide
go.drugbank.com/drugs/DB00606ApprovedThis results in an increase in potassium excretion via the sodium-potassium exchange mechanism. … It is also indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effectiveness of other antihypertensive drugs in the more severe forms of hypertension.
Arbutamine
go.drugbank.com/drugs/DB01102ApprovedArbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in … diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .
Categories: Compounds used in a research, industrial, or household settingSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigational[A242417] Targeting mTOR received more attention especially in cancer, as mTOR signalling pathways are constitutively activated in many types of human cancer. … [A1320] Sirolimus was first approved by the FDA in 1999 for the prophylaxis of organ rejection in patients aged 13 years and older receiving renal transplants.
Molsidomine
go.drugbank.com/drugs/DB09282ApprovedWithdrawnInterestingly, it is being studied as being a preventive measure in cerebral infarction [A31932]. … Molsidomine is an orally active, long-acting vasodilator, which belongs to the class of medications known as syndnones.
Categories: Vasodilators Used in Cardiac DiseasesUndecylenic acid
go.drugbank.com/drugs/DB11117ApprovedIt is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones [L1891]. … Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat.
Mixtures: Desenex Medicated Spray-ON Powder, Desenex Medicated Spray-ON PowderProducts: Pinceladas Goyescas Original Brush on FungicideOlsalazine
go.drugbank.com/drugs/DB01250Approved[A257063] Olsalazine is used in the treatment of ulcerative colitis.[L45023,L45151] … [A257078] Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon.
Thrombin
go.drugbank.com/drugs/DB11300ApprovedInvestigationalMedical thrombin is a protein substance produced through a conversion reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the presence of calcium chloride. … Also known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation.
Mixtures: TACHOSİL 5,5 MG/CM2 İNSAN FİBRİNOJENİ VE 2.0 IU/CM2 İNSAN TROMBİNİ İLAÇLI SÜNGERSynonyms: coagulation factor IINitrous acid
go.drugbank.com/drugs/DB09112ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. … There is also research to investigate its applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and Pseudomonas aeruginosa infections.
Categories: Compounds used in a research, industrial, or household setting