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Fondaparinux
go.drugbank.com/drugs/DB00569ApprovedInvestigationalFondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. … angina (UA) and non-ST segment elevation myocardial infarction (NSTEMI); and in the management of ST segment elevation myocardial infarction (STEMI).
Categories: Factor Xa Inhibitors, Indirect factor Xa inhibitorsRopeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α-2b in _Escherichia coli_ that has high tolerability and a long half-life. … [A242015, L39170] Ropeginterferon alfa-2b has shown efficacy in PV in _in vitro_ and _in vivo_ models and clinical trials.
Categories: Interferon Type ISynonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bNevirapine
go.drugbank.com/drugs/DB00238ApprovedInvestigationalA potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS.
Mixtures: Zidovex LN (Lamivudine 150mg, Zidovudine 300mg, Nevirapine 200mg Tablets), ZIMODINE N ®Categories: Antivirals used in combination for the treatment of HIV infectionsNalmefene
go.drugbank.com/drugs/DB06230ApprovedInvestigationalWithdrawnNalmefene, a 6-methylene analogue of [naltrexone], is an opioid receptor antagonist. … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor.
Categories: Drugs Used in Alcohol Dependence, Drugs Used in Addictive DisordersGrazoprevir
go.drugbank.com/drugs/DB11575ApprovedIn a joint recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) recommend Grazoprevir as first line therapy … in combination with [DB11574] for genotypes 1a, 1b, and 4 of Hepatitis C [A19593].
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsProcaine benzylpenicillin
go.drugbank.com/drugs/DB09320ApprovedVet approvedIt is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. … This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection of penicillin. It is widely used in veterinary settings.
Mixtures: Bicillin A-P Injection Pws, SENCAIN-S 100.000 IU/300.000 IU IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPULEpcoritamab
go.drugbank.com/drugs/DB16672ApprovedInvestigational[L46516] It is administered subcutaneously and is currently being evaluated as a monotherapy and in combination for the treatment of a variety of hematologic malignancies. … Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).
Thyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831] Thyroid extract is no longer considered a first line therapy as it delivers a dose that is inconsistent with the stated strength of the tablet. … [A190813] Thyroid extracts were never FDA approved as their use in the United States predates the FDA.[A190831]
Tyrothricin
go.drugbank.com/drugs/DB13503ApprovedWithdrawnand 40% neutral linear gramicidins (where valine-gramicidin A is often the major gramicidin present, although the mixture composition can vary) [L4019, L4021, L4022]. … do exist [L4028].
Latanoprostene bunod
go.drugbank.com/drugs/DB11660ApprovedIn comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. … Conversely however, latanoprostene bunod integrates an NO-donating moiety in lieu of the isopropyl ester typically found in latanoprost.