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Glecaprevir
go.drugbank.com/drugs/DB13879ApprovedInvestigationalIn cell cultures, the emergence of amino acid substitutions at NS3 resistance-associated positions A156 or D/Q168 in HCV genotype 1a, 2a or 3a replicons led to reduced susceptibility to glecaprevir [FDA … patients with moderate to severe kidney disease and those who are on dialysis [L940].
Categories: Antivirals for treatment of HCV infectionsSpectinomycin
go.drugbank.com/drugs/DB00919ApprovedVet approvedWithdrawnAn antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Hydroxyamphetamine
go.drugbank.com/drugs/DB09352ApprovedThe main use of hydroxyamphetamines as eye drops is the diagnosis of Horner's syndrome which is characterized by nerve lesions. … Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry mouth, headache, increased sensitivity of eyes to sunlight, muscle stiffness or tightness and temporary
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: dl-4-hydroxyamphetamine, dl-p-hydroxyamphetaminePirbuterol
go.drugbank.com/drugs/DB01291ApprovedWithdrawnIn vitro studies and in vivo pharmacologic studies have demonstrated that pirbuterol has a preferential effect on beta-2 Adrenergic receptors compared with isoproterenol. … Increased c-AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
Categories: Compounds used in a research, industrial, or household settingHuman cytomegalovirus immune globulin
go.drugbank.com/drugs/DB13886ApprovedInvestigationalDuring the span of an individual's life, the virus may reactivate, resulting in repeated shedding and spread of the virus. … Cytomegalovirus (CMV) may lead to a wide spectrum of infection in immunocompetent hosts.
Products: MEGALOTECT CP SOLUTION FOR INFUSION 100 U/MLVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalIn addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … become aggressive or black out.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceSafinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalSafinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: XADAGO 100 MG TABLETASRECUBIERTAS CON PELÍCULA, XADAGO 50 MG TABLETAS RECUBIERTAS CON PELÍCULAPolycarbophil
go.drugbank.com/drugs/DB09311ApprovedWithdrawnThis drug may also be used to help relieve the symptoms of irritable bowel syndrome or diarrhea. … The material possesses exceptionally high water-binding capacity. is not absorbed, does not interfere with the activity of digestive enzymes or intestinal absorption, possesses satisfactory stability,
Categories: Compounds used in a research, industrial, or household settingPholcodine
go.drugbank.com/drugs/DB09209ApprovedIllicit[A31738] Pholcodine activity is the suppression of unproductive cough and it also has a mild sedative effect with little or no analgesic effects. … It belongs to the opioid family of compounds and it is widely used.
Categories: Heterocyclic Compounds with 4 or More RingsMetronidazole
go.drugbank.com/drugs/DB00916ApprovedInvestigationala wide variety of infections. … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.
Mixtures: METARSAL N CAPSULAS, OVAZOL CON NISTATINA OVULOSCategories: combinations of imidazole derivatives