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Setmelanotide
go.drugbank.com/drugs/DB11700ApprovedInvestigational[A224449] Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. … [L24474] It is an agonist of the melanocortin 4 receptor.
Salts: Setmelanotide acetateCategories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsBulevirtide
go.drugbank.com/drugs/DB15248ApprovedInvestigationalHepatitis D is considered the most severe type of viral hepatitis and leads to the rapid development of cirrhosis, severe decompensation of liver function, and an increased risk of mortality. … [L30215] In the USA, bulevirtide has been granted Orphan Drug Designation and Breakthrough Therapy Designation.
Salts: Bulevirtide acetateCategories: Amino Acids, Peptides, and ProteinsNafarelin
go.drugbank.com/drugs/DB00666ApprovedInvestigationalNafarelin has been used in the treatments of central precocious puberty and endometriosis.
Salts: Nafarelin acetateCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders.
Salts: Fluorometholone acetateCategories: fluorometholone and mydriatics, fluorometholone and antibioticsIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B<sub>2</sub> receptors antagonists, thus representing a new class of medication.
Salts: Icatibant acetateCategories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsPeginesatide
go.drugbank.com/drugs/DB08894ApprovedWithdrawnThe polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life. … Peginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine. FDA approved March 27, 2012.
Salts: Peginesatide acetateCategories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsZiconotide
go.drugbank.com/drugs/DB06283ApprovedInvestigational[A202835, L13389] Other such peptides, collectively termed conotoxins, exist, and some have shown efficacy in binding specific subsets of calcium channels; ziconotide is used in part because it can be
Salts: Ziconotide acetateCategories: Fluids and Secretions, Calcium-Regulating Hormones and AgentsTetracosactide
go.drugbank.com/drugs/DB01284ApprovedInvestigationalTetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all...
Salts: Tetracosactide acetateCategories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsEthynodiol diacetate
go.drugbank.com/drugs/DB00823ApprovedA synthetic progestational hormone used alone or in combination with estrogens as an oral contraceptive. … Although etynodiol or ethynodiol are sometimes used as a synonym for ethynodiol diacetate, what is usually being referred to is actually ethynodiol diacetate and not ethynodiol (which is a separate drug
Mixtures: Ethynodiol Diacetate and Ethinyl Estradiol, Ethynodiol Diacetate and Ethinyl EstradiolCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemCalendula officinalis flower
go.drugbank.com/drugs/DB14263ApprovedIt is not an approved drug.
Synonyms: Calendula Officinalis Flower Water