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Allantoin
go.drugbank.com/drugs/DB11100ApprovedInvestigationalIn human muscle, urate is oxidized to allantoin during such exercise [FDA Label]. … Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label].
Benazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure . Upon cleavage of its ester group by the liver, benazepril is converted into its acti...
Calaspargase pegol
go.drugbank.com/drugs/DB14730ApprovedInvestigationalCalaspargase pegol, by _Shire_ pharmaceuticals, was approved by the FDA on December 20, 2018 for acute lymphoblastic anemia (ALL) [L4890]. … L-asparagine amidohydrolase) and monomethoxypolyethylene glycol (mPEG) with a succinimidyl carbonate (SC) linker to create a stable molecule which increases the half-life and decreases the dosing frequency [FDA
Technetium Tc-99m tilmanocept
go.drugbank.com/drugs/DB09266ApprovedDTPA serves as a chelating agent for technetium Tc 99m to bind [FDA Label]. … Food and Drug Administration (FDA) for the imaging of lymph nodes with or without scintigraphic imaging.
Eravacycline
go.drugbank.com/drugs/DB12329ApprovedInvestigationalIt was first approved by the FDA on August 27, 2018 [L4540].
Dasabuvir
go.drugbank.com/drugs/DB09183ApprovedApproved in December 2014 by the FDA, Viekira Pak is indicated for the treatment of HCV genotype 1a with [DB00811] or genotype 1b without [DB00811] [FDA Label]. … Dasabuvir is a non-nucleoside NS5B inhibitor which binds to the palm domain of NS5B and induces a conformational change which renders the polymerase unable to elongate viral RNA [FDA Label].
Efmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalrFVIII-Fc fusion protein (rFVIIIFc) where the conjugated molecule of rFVIII to polyethylene glycol is covalently fused to the dimeric Fc domain of human immunoglobulin G1, a long-lived plasma protein [FDA
Gabapentin
go.drugbank.com/drugs/DB00996ApprovedInvestigationalGabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment o...
Products: NEURONTIN 800MG FTA, Nra-gabapentinPeginterferon alfa-2a
go.drugbank.com/drugs/DB00008ApprovedInvestigationalApproved in 2002 by the FDA, Pegasys is indicated for the treatment of HCV with [DB00811] or other antiviral drugs [FDA Label].
Desogestrel
go.drugbank.com/drugs/DB00304ApprovedInvestigational[A176342] The first approved drug containing desogestrel was developed by Organon USA Inc in 1972 and FDA approved in 1992.[L5762]