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Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[A7935] It was first described in the literature in 2010 as a monoclonal antibody that targets CD38+ multiple myeloma cells; the first of its kind. … [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs.
Products: Darzalex 20mg/mL Concentrate for Solution for Infusion, DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5MLAmitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in...
Products: AMITRIPTYLIN SDZ 100MG RET, Elavil Tablet 10mgRupatadine
go.drugbank.com/drugs/DB11614ApprovedInvestigationalIt was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and liquid formulation for pediatric use.
Products: RUPAFIN 10MG, URTIMED 10MGPerampanel
go.drugbank.com/drugs/DB08883ApprovedInvestigationalIt is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
Products: FYCOMPA FILM-COATED TABLET 10MG, Fycompa 10mg Film-coated TabletsFosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalIt is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Mixtures: FOSINOPRIL E IDROCLOROTIAZIDE AUROBINDO, FOSINOPRIL E IDROCLOROTIAZIDE AUROBINDOProducts: FOSINORM 10MG, Monopril Tab 10mgDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: COSOPT 20MG/ML+5MG/ML, COSOPT 20MG/ML+5MG/MLProducts: Dorzolamide Hydrochloride Ophthalmic Solution 2%, 10mL Ophthalmic Solution 2%, 10mL, TRUSOPT 20MG/MLAcetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedIt should be kept out of reach from young children, toddlers, and infants [FDA label].
International brands: St. Joseph Aspirin for AdultsMixtures: TRINOMIA HARD CAPSULES 100mg/ 20mg/ 10mg, TRINOMIA HARD CAPSULES 100mg/ 20mg/ 5mgOxazepam
go.drugbank.com/drugs/DB00842Approved[A203516] It is an active metabolite of both [diazepam] and [temazepam][A39486] and undergoes very little biotransformation following absorption, making it unlikely to participate in pharmacokinetic interactions
Products: OXA - CT 10MG, OXA - CT 50MGCladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigationalCladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes. … [A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell
Products: Mavenclad 10mg Tablets, MAVENCLAD TABLET 10MGSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigationalIt binds to mineralocorticoid receptors and functions as aldosterone antagonists.[A178192] It promotes sodium and water excretion and potassium retention. … [A11837, A178246] It is indicated to treat several conditions, including heart failure, edema, hyperaldosteronism, and hypertension.
Mixtures: SPIRO COMP RATIO 50MG/20MG, SPIRO COMP RATIO 50MG/20MGProducts: SPIRO - CT 50MG TABLETTEN, SPIRO - CT 100MG TABLETTEN