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Displaying results 161 - 170 of 9699 in total
  1. Drug

    Pravastatin

    go.drugbank.com/drugs/DB00175
    ApprovedInvestigational

    [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained. … It was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co.

    Products: LEMMA-LD, PRAVASTATIN 1A PHARMA 10MG
  2. Drug

    Levodopa

    go.drugbank.com/drugs/DB01235
    ApprovedInvestigational

    Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. … The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133].

    Mixtures: MADOPAR LT, MADOPAR LTSynonyms: L-DOPA, 3-Hydroxy-L-tyrosine
  3. Drug

    Clonazepam

    go.drugbank.com/drugs/DB01068
    ApprovedIllicitInvestigational

    A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. … Now available as a generic medication, the agent continues to see exceptionally high use as millions of prescriptions are written for the medication internationally every year.

  4. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality

    Mixtures: PLENACOR LP, Aa-atenidoneProducts: CORATEN PA, ATENOLOL AL 25
  5. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].

    Products: Azithromycin film-coated tablets 500mg Lesvi Lab, Azithromycin Powder For Oral Suspension 200mg/5ml Lesvi Lab
  6. Drug

    Benserazide

    go.drugbank.com/drugs/DB12783
    ApprovedInvestigational

    When levodopa is used by itself as a therapy for treating Parkinson's disease, its ubiquitous metabolism into dopamine is responsible for a resultant increase in the levels of circulating dopamine in the … This can result in a number of side effects like nausea, vomiting, or even cardiac arrhythmias that may diminish patient adherence [F2, L2553].

    Mixtures: MADOPAR LT, MADOPAR LTCategories: Aromatic L-amino Acid Decarboxylase Inhibitors
  7. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    [L40714] Human G-CSF is a glycoprotein that regulates the production and release of neutrophils from the bone marrow. … [L40773] A long-acting, pegylated G-CSF, [pegfilgrastim], was made available to increase the duration of action of the drug.

    Products: IOR-LC, ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML
  8. Drug

    Gliclazide

    go.drugbank.com/drugs/DB01120
    ApprovedInvestigational

    a sulfonamide group able to release a proton and the presence of one aromatic group. … [A39546] On the other hand, based on the pharmacological efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and a shorter half-life.

    Products: GLICLAZIDE ZENTIVA LAB
  9. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.

    Mixtures: METOPROLOLSUC 1A PL95/12.5, METOPROLOLSUC 1A PL95/12.5Products: Metoprolol-L, Ag-metoprolol-L
  10. Drug

    Adenosine

    go.drugbank.com/drugs/DB00640
    ApprovedInvestigational

    The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though i...

    Mixtures: Green Tea Eye Ge l, Roselle Tea Eye Ge LProducts: NoTS Li p Shimmer Gloss, Mizon Snail Recovery Ge L Crea M