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Pioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence … failure, bladder cancer) and the availability of safer and more effective alternatives for patients with type 2 diabetes mellitus.
Mixtures: Actoplus Met XR, Actoplus Met XRCategories: Drugs Used in DiabetesThrombin
go.drugbank.com/drugs/DB11300ApprovedInvestigationalThrombin requires no intermediate physiological agent for its action. It clots the fibrinogen of the blood directly. … Patients who are know or suspected to have antibodies to bovine thrombin and/or bovine factor V should not be re-exposed to the product [FDA Label].
Mixtures: Artiss Solutions for Sealant, Deep Frozen, TACHOSİL 5,5 MG/CM2 İNSAN FİBRİNOJENİ VE 2.0 IU/CM2 İNSAN TROMBİNİ İLAÇLI SÜNGERSynonyms: coagulation factor IIErdafitinib
go.drugbank.com/drugs/DB12147ApprovedInvestigational[L5956, L5959] At the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a companion diagnostic with erdafitinib for selecting patients for the indicated therapy … In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for
Maftivimab
go.drugbank.com/drugs/DB15899ApprovedInvestigational[A221825, A221830] A recent large-scale study elucidated that both neutralizing and Fc-mediated functions of antibodies were important for therapeutic benefit in animal models of EBOV infection. … [A222078] The chief surface target of EBOV particles is the GP<sub>1,2</sub> glycoprotein, which also appears on the surface of EBOV-infected cells, offering opportunities for both neutralizing and cytotoxic
Categories: Treatments for Ebola Virus DiseaseN-acetyltyrosine
go.drugbank.com/drugs/DB11102ApprovedInvestigationalN-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. [DB00135] is a non-essential amino acid with a polar side group. … N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine [A32652].
Mixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseSynonyms: N-acetyltyrosin, N-acetyltyrosineClavulanic acid
go.drugbank.com/drugs/DB00766ApprovedInvestigationalVet approved[A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav, or Clavulin.[L7880,L7904,L7910] … Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin] to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening
Mixtures: Co-Amoxiclav for Injection 1.2g, JULMENTIN (2X 457 MG/5ML POWDER FOR SUSPENSION)Alimentary Obesity
go.drugbank.com/conditions/DBCOND0061821Synonyms: Alteration in nutrition: more than body requirements (finding)Ritonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalWhile ritonavir is not an active antiviral agent against hepatitis C virus (HCV) infection, it is added in combination therapies indicated for the treatment of HCV infections as a booster. … Ritonavir is combined with other drugs to treat coronavirus disease 2019 (COVID-19) in patients at risk for progressing into a severe form of the disease, such as [nirmatrelvir].[L40094]
Mixtures: VIRONTAR N COMPRIMIDOS RECUBIERTOS, VIRONTAR N COMPRIMIDOS RECUBIERTOSCategories: Antivirals used in combination for the treatment of HIV infections, Antivirals for Systemic UseBioallethrin
go.drugbank.com/drugs/DB13746ApprovedWithdrawnA mixture of the two same stereoisomers, but in an approximate ratio of R:S in 1:3, is called esbiothrin. … A mixture containing only S-forms of allethrin is referred to as esbioallethrin or S-bioallethrin.
Mixtures: Para Special Shampoo for Lice & NitsCategories: Compounds used in a research, industrial, or household settingMagnesium phosphate
go.drugbank.com/drugs/DB13862InvestigationalSynonyms: Phosphoric acid, magnesium salt (2:3)