Search
Magnesium trisilicate
go.drugbank.com/drugs/DB09281ApprovedMagnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.
Mixtures: ALLUMAG MPS TABLET, ALUSIL MPS TABLETIndomethacin
go.drugbank.com/drugs/DB00328ApprovedInvestigationalIndometacin was first discovered in 1963 and it was first approved for use in the U.S. by the Food and Drug Administration in 1965, [A486] along with other acetic acid derivatives such as [diclofenac] … Although deemed effective in reducing ocular inflammation in clinical studies, topical NSAIDs were also associated with a potential reduction in corneal sensitivity accompanied by an increased risk of
Mixtures: INDAFLEX-IBTizanidine
go.drugbank.com/drugs/DB00697ApprovedInvestigationalInitially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons … It may also be caused by musculoskeletal injury [A177583]. Regardless of the cause, muscle spasticity can be an extremely painful and debilitating condition.
Categories: Adrenergic alpha-2 Receptor AgonistsDosulepin
go.drugbank.com/drugs/DB09167ApprovedInvestigationalDosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South … It is not FDA-approved due to low therpeutic index and significant toxicity in overdose.
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsPegulicianine
go.drugbank.com/drugs/DB18731ApprovedInvestigationalPegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. … [L50537] The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments that emit a fluorescent signal that can be detected using a fluorescence imaging device.
Categories: Compounds used in a research, industrial, or household settingFerrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Mixtures: Vc II, Iron IITyrothricin
go.drugbank.com/drugs/DB13503ApprovedWithdrawnand 40% neutral linear gramicidins (where valine-gramicidin A is often the major gramicidin present, although the mixture composition can vary) [L4019, L4021, L4022]. … Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus
Ancrod
go.drugbank.com/drugs/DB05099ApprovedWithdrawnCurrently, Viprinex®/ancrod is not approved or marketed in any country, but is being investigated as a stroke treatment in worldwide clinical trials. In January 2005, the U.S. … Ancrod, marketed as Viprinex, is a defibrinogenating agent derived from Malayan pit viper venom. The defribrinogenation of blood results in an anticoagulant effect.
Endothelin receptor type B
go.drugbank.com/bio_entities/BE0000043TargetHumansNon-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Endothelin receptor type BSynonyms: Endothelin receptor non-selective typeMuscarinic acetylcholine receptor M3
go.drugbank.com/bio_entities/BE0000045TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M3