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Aprotinin
go.drugbank.com/drugs/DB06692ApprovedInvestigationalWithdrawnFor this use, it is typically administered by injection. … The goal of using of aprotinin was subsequently to minimize end-organ damage resulting from hypotension due to blood loss in surgery and to reduce the necessity for blood transfusions during surgery.
Mixtures: ARTISS SOLUTIONS FOR SEALANT, DEEP FROZEN, Artiss Solutions for Sealant, Deep FrozenOzenoxacin
go.drugbank.com/drugs/DB12924Approveds Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age … To date, ozenoxacin has been used in trials studying the treatment of impetigo. As of December 11, 2017 the FDA approved Ferrer Internacional S.A.'
Categories: Antibiotics for Topical UseAndexanet alfa
go.drugbank.com/drugs/DB14562ApprovedAndexanet alfa retains the structural similarity to that of endogenous human factor Xa, but exists in its mature functional form without the need for activation via the intrinsic or extrinsic coagulation … However, the use of these agents is associated with a risk for uncontrollable bleeding episodes that can lead to can cause serious or fatal bleeding.
Tabelecleucel
go.drugbank.com/drugs/DB17072ApprovedInvestigationalBoth T-cells and B-cells are obtained from the same donor, and T-cells are grown to increase their numbers. … It is produced by mixing T-cells with B-cells that have been infected with the Epstein-Barr virus (EBV).
Methyl nicotinate
go.drugbank.com/drugs/DB13882ApprovedFor veterinary purposes, methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and muscle and joint pains [F64]. … The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.
Mixtures: ALGOFLEX SAME, Arthricare for Women NighttimeClascoterone
go.drugbank.com/drugs/DB12499ApprovedInvestigational[A218771] By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland … It binds to androgen receptors with high affinity.
Categories: Anti-Acne Preparations for Topical UseBenserazide
go.drugbank.com/drugs/DB12783ApprovedInvestigationalA decarboxylase inhibitor like benserazide is consequently an effective compound to combine with levadopa as it is incapable of crossing the blood-brain barrier itself but acts to prevent the formation … Moreover, the European Medcines Agency has conferred an orphan designation upon benseraside since 2015 for its potential to be used as a therapy for beta thalassaemia as well [F3].
Mixtures: MADOPAR 125 T, MADOPAR 125 TOrnidazole
go.drugbank.com/drugs/DB13026InvestigationalOrnidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: ORNIDONE FORT 500 MG FILM TABLET, 10 ADET, ORNISID FORT 500 MG FİLM KAPLI TABLET, 10 ADETRabeprazole
go.drugbank.com/drugs/DB01129ApprovedInvestigationalIt is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form.
Mixtures: RASOFORCE 20/1680 MG TOZ İÇEREN SAŞE, 14 SAŞE, RASOFORCE 20/1680 MG TOZ İÇEREN SAŞE, 28 SAŞECategories: Drugs for Acid Related Disorders, Topical Products for Joint and Muscular PainMitapivat
go.drugbank.com/drugs/DB16236ApprovedInvestigationalDefects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red blood cells, leading to lifelong premature destruction of red blood cells or chronic … to lifelong hemolytic anemia.