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Technetium Tc-99m succimer
go.drugbank.com/drugs/DB09436Approved[L40558] The use of technetium Tc-99m succimer for the detection of kidney cortical defects was first approved by the FDA on February 23, 2022, under the market name NephroScan.[L40573] … It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma scintigraphy or single-photon emission computed tomography (SPECT).
Synonyms: (99m)Tc-DMSA, Technetium tc 99m succimerDanazol
go.drugbank.com/drugs/DB01406ApprovedInvestigationalDanazol has been used in the treatment of endometriosis and some benign breast disorders. … A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins.
Categories: Sex Hormones and Modulators of the Genital SystemPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalA colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Mixtures: Ti Lub Lotion, Veradex-EProducts: Chap-ET, Chap-etCurcumin
go.drugbank.com/drugs/DB11672ApprovedInvestigationalDespite proven efficacy against numerous experimental models, poor bioavailability due to poor absorption, rapid metabolism, and rapid systemic elimination have been shown to limit the therapeutic efficacy … Due to these properties, curcumin has been investigated for the treatment and supportive care of clinical conditions including proteinuria, breast cancer, multiple myeloma, depression, and Non Small Cell
Mixtures: Melittin Joint Soothing GeThalidomide
go.drugbank.com/drugs/DB01041ApprovedInvestigationalWithdrawnDue to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enrol in the THALIDOMID Risk Evaluation and Mitigation Strategy (REMS) program to ensure contraception … A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects.
Gestrinone
go.drugbank.com/drugs/DB11619ApprovedHowever, from 1982 this drug attracted increased interest due to significant therapeutic effects in the treatment endometriosis. … is used primarily in the treatment of endometriosis.
Categories: Sex Hormones and Modulators of the Genital SystemPhentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigational[A174370] Phentermine has not been reported an addictive potential which allows this agent to be classified under the Schedule IV drugs (low abuse potential). … [A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: TERFAMEX TBetrixaban
go.drugbank.com/drugs/DB12364ApprovedBetrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [A7708]. … for VTE [A27285].
Tegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnin female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular event than the broader population. … natural secretions in the gut, among others.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin-4 Receptor AgonistPizotifen
go.drugbank.com/drugs/DB06153ApprovedPizotifen belongs to the class of antamines and is related to [cyproheptadine].[A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. … Some patients receiving pizotifen treatment developed tolerance with the prolonged use of the drug [L2292].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Adrenergic alpha-1 Receptor Antagonists