Technetium Tc-99m succimer is a radioactive diagnostic agent used as an aid in the scintigraphic evaluation of renal parenchymal disorders. It works by binding to the cortical region of the kidneys.
- Mechanism
- Curator reviewed · 4 references
Evaluating the quantity of functional renal tissue is essential in renal parenchymal disorders, as it assesses the patient's ability to maintain renal function. Technetium Tc-99m succimer is used to image the renal cortices in conjunction with gamma scintigraphy or single-photon emission computed tomography (SPECT). Technetium Tc-99m succimer is taken up by tubular cells within the renal cortex regardless of renal flow. Technetium Tc-99m succimer binds to normal renal cortical tissue, distinguishing it from nonfunctioning dysplastic tissue, even in the presence of renal insufficiency.
- Primary indication
- Technetium Tc-99m succimer is a radioactive diagnostic agent indicated for use as an aid in the scintigraphic evaluation of renal parenchymal disorders in adults and pediatric patients including term neonates.Curator reviewed · 1 structured indication
- Formula / weight
- C4H6O4S2Tc · 281.11 g/mol (avg)
- Also known as
- (99m)Tc-DMSA · Technetium (99mTc) succimer · Technetium Tc 99m dimercaptosuccinic acid · Technetium tc 99m succimer
Resolves to
UEGHKGHBANZTIM-SFJYCVELSA-NSMILES[99Tc].OC(=O)[C@@H](S)[C@@H](S)C(O)=OWhat you can answer from here — as of June 15, 2026
Which drugs share a target with Technetium Tc-99m succimer, and which of those have an active Phase 3 trial?
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