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Tazarotene
go.drugbank.com/drugs/DB00799ApprovedTazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids. It is a prodrug that is found in topical formulations used in the treatment of various conditons, such as psoriasis, acne, and...
Mixtures: Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.1%, Hyaluronic Acid Sodium Salt 0.5% / Tazarotene 0.05%Categories: Antipsoriatics for Topical UseZucapsaicin
go.drugbank.com/drugs/DB09120ApprovedWithdrawnZucapsaicin has also been evaluated for the management of several conditions manifested by chronic nerve pain. … Zucapsaicin, the cis-isomer of capsaicin, is a topical analgesic used to treat osteoarthritis of the knee and other neuropathic pain.
Categories: Topical Products for Joint and Muscular PainCetalkonium
go.drugbank.com/drugs/DB11583ApprovedWithdrawn[L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant.[L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113] … [A27143] It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi.
Categories: Compounds used in a research, industrial, or household settingRotigotine
go.drugbank.com/drugs/DB05271ApprovedInvestigationalHowever, all Neupro patches in the United States and some of Europe were recalled in 2008 due to delivery mechanism issues. Rotigotine has been authorized as a treatment for RLS since August 2008. … Rotigotine was developed by Aderis Pharmaceuticals. In 1998 Aderis licensed worldwide development and commercialization rights to Schwarz Pharma of Germany.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCatumaxomab
go.drugbank.com/drugs/DB06607ApprovedWithdrawnCatumaxumab was approved for market in Canada in May 2012 for the same condition [FDA Label]. It is currently available under the brand name Removab. … Catumaxumab was initially authorized for market by the European Medicines Agency in April 2009 for the treatment of malignant ascites [L1122].
Umeclidinium
go.drugbank.com/drugs/DB09076ApprovedInvestigational[A7719] However, even though umeclidinium monotherapy is well-tolerated for up to 14 days, it is more likely to be used in combination therapy, as the international Gold Initiative for Chronic Obstructive … Umeclidinium is a long-acting muscarinic antagonist (LAMA) used as a maintenance treatment for symptoms of chronic obstructive pulmonary disease (COPD).
Categories: Agents to Treat Airway Disease, Drugs for Obstructive Airway DiseasesSpecific infections by free-living amoebae
go.drugbank.com/conditions/DBCOND0089199Drugs: MiltefosineSynonyms: Disease due to Endamoebidae (disorder)Hemorrhagic disease of the newborn
go.drugbank.com/conditions/DBCOND0022633Drugs: PhylloquinoneSynonyms: Hemorrhagic disease of the newborn due to vitamin K deficiency (disorder)Migalastat
go.drugbank.com/drugs/DB05018ApprovedInvestigational[L47036,L47057] Galafold also received Orphan Drug designation, which provides incentives to assist and encourage the development of drugs for rare diseases. … serious conditions where there is an unmet medical need and where a drug is shown to have certain effects that are reasonably likely to predict a clinical benefit to patients.
Reboxetine
go.drugbank.com/drugs/DB00234ApprovedInvestigationalWithdrawnReboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine. … Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra.