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Apalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalApalutamide is the first FDA-approved treatment for non-metastatic, castration-resistant prostate cancer [L1295]. … Apalutamide was approved in February 2018 by the FDA as Erleada for the treatment of patients with non-metastatic prostate cancer that is resistant to treatment with hormone therapy (castration-resistant
Categories: Androgen Receptor InhibitorsAK106-001616
go.drugbank.com/drugs/DB16058InvestigationalAK106-001616 is under investigation in clinical trial NCT01285752 (A Study of AK106-001616 in Patients With Rheumatoid Arthritis (RA)).
Sunvozertinib
go.drugbank.com/drugs/DB18925InvestigationalSunvozertinib is an irreversible and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. … A274143] Sunvozertinib was granted accelerated approval in the US on July 2, 2025 for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor
Categories: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitorsAV608
go.drugbank.com/drugs/DB05072InvestigationalAV608 is a NK-1 antagonist. It is developed for the treatment of Social anxiety disorder (SAD), irritable bowel syndrome (IBS) and overactive bladder (OAB).
Peginterferon alfacon-1
go.drugbank.com/drugs/DB05860Experimental[Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients with chronic hepatitis C infections.
Detomidine
go.drugbank.com/drugs/DB11556InvestigationalVet approvedCurrently, it is only approved by the FDA for use in horses but has been studied for use in other large animals.
Categories: Adrenergic alpha-2 Receptor AgonistsBermekimab
go.drugbank.com/drugs/DB14947InvestigationalBermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Synonyms: RA-18C3CH-1504 L-isomer
go.drugbank.com/drugs/DB19052InvestigationalCH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Etryptamine
go.drugbank.com/drugs/DB01546ApprovedIllicitWithdrawn1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA
Rifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawn[A39986] Rifamycin was further developed by Cosmo Technologies Ltd and approved in November 16, 2018 by the FDA as a prescription drug after being granted the designation of Qualified Infectious Disease