Search
Rabies immune globulin, human
go.drugbank.com/drugs/DB11603ApprovedIMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced … Since rabies vaccine-induced antibody begins to appear within one week, there is no value in administering rabies immune globulin more than eight days after rabies vaccination has begun.
Phloxine B
go.drugbank.com/drugs/DB13911ApprovedWithdrawnPhloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing
Categories: Compounds used in a research, industrial, or household settingSynonyms: D&C Red No. 28Polysorbate 80
go.drugbank.com/drugs/DB11063ApprovedInvestigationalA substance that would not normally dissolve in a particular solution is able to dissolve with the use of a solubilizing agent. … Polysorbate 80 is a hydrophilic nonionic surfactant. It is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops.
Categories: Compounds used in a research, industrial, or household settingApremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigational[L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and … Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases.
Synonyms: N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamideacetylleucyl-leucyl-norleucinal
go.drugbank.com/drugs/DB07558ExperimentalSynonyms: N-Ac-Leu-leu-norleucinal, N-acetylleucylleucylnorleucinalCategories: NF-kappa B, antagonists & inhibitorsBelumosudil
go.drugbank.com/drugs/DB16703ApprovedInvestigational[A236634] It is an inhibitor of rho-associated coiled-coil-containing protein kinases (ROCK), with significantly more selectivity for ROCK2 as compared to ROCK1 (IC<sub>50</sub> 100 nM vs. 3 μM, respectively … [L34749] In the treatment of GVHD, a condition in which donor T-cells begin to attack recipient tissues following allogeneic hematopoeitic stem cell transplantation (HSCT), belumosudil helps to resolve
Idelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalIdelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic … For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab alone would be considered appropriate therapy due to other
Categories: Class Ia Phosphatidylinositol 3-Kinase, antagonists & inhibitors, P-glycoprotein substrates with a Narrow Therapeutic IndexUlobetasol
go.drugbank.com/drugs/DB00596ApprovedUlobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].
Melphalan flufenamide
go.drugbank.com/drugs/DB16627ApprovedWithdrawnMelphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan]. … [A230123] The increased potency makes melphalan flufenamide a treatment option for patients with relapsed or refractory multiple myeloma who have attempted at least 4 lines of therapy already.
Iberdomide
go.drugbank.com/drugs/DB12101Investigationalproteasome inhibitor and an immunomodulatory agent. … Iberdomide is an orally administered cereblon-modulating protein degrader (CELMoD) used to treat multiple myeloma.