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Trastuzumab emtansine
go.drugbank.com/drugs/DB05773ApprovedInvestigationalTrastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic
Products: KADCYLA 100 MG IV INFUZYONLUK COZELTI KONSANTRESI ICIN TOZ, Kadcyla 100 mg powder for concentrate for solution for infusionCeftizoxime
go.drugbank.com/drugs/DB01332ApprovedWithdrawnIt has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Synonyms: syn-7-(2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid, 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acidProducts: E-ZOX, CEFIZOX 500 MG FLAKON, 1 ADETHemoglobin glutamer-250 (bovine)
go.drugbank.com/drugs/DB19235InvestigationalHemoglobin glutamer-250 (bovine) is under investigation in clinical trial NCT00300040 (Safety/feasibility Study of HBOC-201 in Amputation At/below Knee From Critical Lower Limb Ischemia).
Synonyms: Hemoglobin-based oxygen carrier 201 is purified, glutaraldehyde-polymerized, bovine hemoglobin, mw 250000Vismodegib
go.drugbank.com/drugs/DB08828ApprovedInvestigationalAfterwards, it is silenced in all cells and tissues, except for hair, skin and stem cells. … The Hedgehog signaling pathway plays an important role in the development of organs and tissues during embryogenesis.
Synonyms: 2-chloro-N-(4-chloro-3-pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide, Benzamide, 2-chloro-N-(4-chloro-3-(2-pyridinyl)phenyl)-4-(methylsulfonyl)-Products: Erigib 150 mg Sert Kapsül, 28 ADET, ERIVEDGE 150 MG SERT KAPSÜL ,28 KAPSÜLEconazole
go.drugbank.com/drugs/DB01127ApprovedIt is used topically in dermatomycoses also orally and parenterally.
Mixtures: TRILON-E CREAMProducts: Pevaryl 10 mg/g Creme, Gyno-Pevaryl 10 mg/g VaginalcremeAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceutical[A234044] It plays an essential function in calcium homeostasis and bone metabolism. … Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones.
Products: ALPHA D3 0.25 MCG YUMUŞAK KAPSUL, 100 ADET, ONE-ALPHA DROPS 2 mcg/mlNaratriptan
go.drugbank.com/drugs/DB00952ApprovedNaratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Synonyms: N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide, N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamideProducts: NARAMIG TABLETS 2.5 mg, NARAMIG TABLETAS 2.5 MGPimecrolimus
go.drugbank.com/drugs/DB00337ApprovedInvestigationalPimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. … It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Categories: Skin and Mucous Membrane AgentsProducts: Elidel 10 mg/g Creme, ELIDEL %1 KREM, 15 GAcalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigational[L42795,L42800] Unlike Calquence capsules, the co-administration of Calquence tablets and PPIs does not have an effect in the pharmacokinetics of acalabrutinib. … To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others.
Products: CALQUENCE 100 MG SERT KAPSÜL, 60 ADET, CALQUENCE 100 MG SERT KAPSÜL, 56 ADETDisulfiram
go.drugbank.com/drugs/DB00822ApprovedInvestigationalA carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol.
Categories: Drugs Used in Alcohol Dependence, Drugs Used in Addictive DisordersSynonyms: N,N,N',N'-tetraethylthiuram disulfide, 1,1'-dithiobis(N,N-diethylthioformamide)